Allergenic foods from a regulatory perspective: a review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i1.11541

Keywords:

Food allergy; Allergenic foods; Labeling; Legislation.

Abstract

Food allergy is an immunoreaction resulted by the ingestion of allergenic food by sensitive persons. It can result in less severe symptoms, like gastrointestinal and skin manifestations, but also can lead to great health hazardous as anaphylaxis. Once there is no cure to food allergies yet and the treatments available are not safe and effective enough, allergen avoidance is the more appropriate intervention. Therefore, allergic individuals rely on labelling information to make safer choices regarding food consumption. Because of this, many countries decided to establish mandatory declaration of major allergenic food within the label of pre-package food products. This work presents an analysis of the regulatory aspects of this theme in different countries. It was possible to evidence the evolution of regulatory requirements, although substantial differences are unfavorable to international trade and food safety.

References

Agência Nacional de Vigilância Sanitária (ANVISA). (2002). Resolução RDC nº 259, de 20 de setembro de 2002. Regulamento Técnico sobre Rotulagem de Alimentos Embalados. Brasília, DF.

Agência Nacional de Vigilância Sanitária (ANVISA). (2015a). Resolução RDC nº 26, de 02 de julho de 2015. Dispõe sobre os requisitos para rotulagem obrigatória dos principais alimentos que causam alergias alimentares. Brasília, DF.

Agência Nacional de Vigilância Sanitária (ANVISA). (2015b). Relatório de Análise de Contribuições em Consulta Pública e Audiência Pública. http://antigo.anvisa.gov.br/documents/33880/2552856/Relat%C3%B3rio+de+An%C3%A1lise+de+Contribui%C3%A7%C3%B5es+da+CP+29-2014/ca bfa4dc-440b-4841-a713-10e8ddd77838.

Agência Nacional de Vigilância Sanitária (ANVISA). (2017 a). Perguntas e Respostas sobre Rotulagem de Alimentos Alergênicos. (5a ed.), Brasília. 2017. https://www.gov.br/anvisa/pt-br/centraisdeconteudo/publicacoes/alimentos/perguntas-e-respostas/rotulagem-de-alergenicos.pdf.

Agência Nacional de Vigilância Sanitária (ANVISA). (2017 b). Resolução RDC nº 136, de 08 de fevereiro de 2017. Estabelece os requisitos para declaraçãoobrigatória da presença de lactose nos rótulosdos alimentos. Brasília, DF.

Agência Nacional de Vigilância Sanitária (ANVISA). (2018). Guia sobre Programa de Controle de Alergênicos. Guia n° 05/2018 – Versão 2. 2018. http://antigo.anvisa.gov.br/documents/10181/2779039/%281%29Guia+Programa+Controle+de+Alergenicos+versao+2.pdf/69af35f5-cc11-412e-ade5-4d47fef14f5e.

Agência Nacional de Vigilância Sanitária (ANVISA). (2019). Guia para Comprovação da Segurança de Alimentos e Ingredientes. http://antigo.anvisa.gov.br/documents/10181/5355698/Guia+Seguran%C3%A7a+de+Alimentos.pdf/dae93caa-7418-4b9a-97f2-2ec9ebc139e2

Aiking, H., Boer, J. (2020). The next protein transition. Trends in Food Science & Technology, 105, 515-522.

Allen, K. J., et al. (2014). Precautionary labelling of foods for allergen content: are we ready for a global framework? World Allergy Organization Journal, 7(10), 1-14.

Allergen Bureau. (2020). Food Industry Guide to the Voluntary Incidental Trace Allergen Labelling (VITAL) Program Version 3.0. Austrália e Nova Zelândia. October 2012. http://allergenbureau.net/wp-content/uploads/2020/10/Food_Industry_Guide_VITAL_Program_Version_October_2020_VF1.pdf

ASBAI. Associação Brasileira de Alergia e Imunopatologia. (2018). Consenso Brasileiro sobre Alergia Alimentar: Parte 1 - Etiopatogenia, clínica e diagnóstico. Arquivos de Asma Alergia e Imunologia, 2(1).

Australia New Zealand Food Standards Code. (2011). Standard 1.2.3 - Mandatory Warning and Advisory Statements and Declarations. https://www.legislation.gov.au/Details/F2011C00610.

Barnett, J., et al. (2011). How do peanut and nut-allergic consumers use information on the packaging to avoid allergens? Allergy, 66, 969-978.

Bernardo, F. (2006). Perigos sanitários nos alimentos. Revista Segurança e Qualidade Alimentar, 1, 3-7.

Besler, M. Determination of allergens in foods. TrAC Trends in Analytical Chemistry, 20(11), 662-672.

Boyce, J. A., et al. Guidelines for the diagnosis and management of food allergy in the United States: Summary of the NIAID- Sponsored Expert Panel Report. Nutrition, 27(2), 253-267.

Brandtzaeg, P. Food allergy: separating the science from the mythology. Nature Reviews Gastroenterology and Hepatology, 7(7), 380-400.

Codex Alimentarius Commission. (1993). Report of the Twenty-Second Session of the Codex Committee on Food Labelling. http://www.fao.org/fao-who-codexalimentarius/meetings-reports/en/?y=1993&s=1991.

Codex Alimentarius Commission. (2018). Report of The Forty-Fourth Session of The Codex Committee On Food Labelling. http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-714-44%252FREPORT%252FREP18_FLe.pdf.

Codex Alimentarius Commission. (2019). Discussion Paper on Allergen Labelling http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-714-45%252Fdocuments%252Ffl45_08e.pdf

Codex Alimentarius. (2001). Codex Alimentarius - Food Labeling - Complete Texts – Revised 2001. http://www.fao.org/docrep/005/Y2770E/ y2770e00.htm#Contents.

European Parliament. (2003). Directive 2003/89/EC of the European Parliament and of the Council of 10 November 2003. Amending Directive 2000/13/EC as regards indication of the ingredients present in foodstuffs. Official Journal of the European Union. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L: 2003:308:0015:0018:EN:PDF

European Parliament. (2006). Commission Directive 2006/142/EC of 22 December 2006. Amending Annex IIIa of Directive 2000/13/EC of the European Parliament and of the Council listing the ingredients which must under all circumstances appear on the labelling of foodstuffs. Official Journal of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=OJ:L:2006:368:FULL&from=PT

European Parliament. (2007). Commission Directive 2007/68/EC of 27 November 2007. Amending Annex IIIa to Directive 2000/13/EC of the European Parliament and of the Council as regards certain food ingredients. Official Journal of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32007L0068&from=EN

European Parliament. (2011). Regulation (Eu) No 1169/2011 of the European Parliament and of the Council of 25 October 2011. On the provision of food information to consumers, amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004. http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32011R1169&from=EN

Fda - Food and Drug Administration. (1996). Allergens - Label Declaration of Allergenic Substances in Foods; Notice to Manufacturers. 1996. http://www.fda.gov/food/guidanceregulation/

Fda - Food and Drug Administration. (2001). Compliance Policy Guide Sec. 555.250 Statement of Policy for Labeling and Preventing Cross-contact of Common Food Allergens. 2001. http://www.fda.gov/ICECI/ComplianceManuals/CompliancePolicyGuidanceManual/ucm074552.htm

Fda - Food and Drug Administration. (2004). Food Allergen Labeling and Consumer Protection Act of 2004. https://www.fda.gov/media/77570/download

Fda - Food and Drug Administration. (2020 a). Inventory of Notifications Received under 21 U.S.C. 343(w)(7) for Exemptions from Food Allergen Labeling. Online. https://www.fda.gov/food/food-labeling-nutrition/inventory-notifications-received-under-21-usc-343w7-exemptions-food-allergen-labeling

Fda - Food and Drug Administration. (2020 b). Inventory of Petitions Received under 21 U.S.C. 343(w)(6) for Exemptions from Food Allergen Labeling. Online. https://www.fda.gov/food/food-labeling-nutrition/inventory-petitions-received-under-21-usc-343w6-exemptions-food-allergen-labeling

Food Safety Authority of Ireland. (2011). Food Allergens & Labelling Survey June 2011. https://www.fsai.ie/resources.../allergen_labelling _2011.html.html

Fsa - Food Standards Agency. (2015). Allergy: what to consider when labelling food. Reino Unido. 2015. https://www.food.gov.uk/sites/default/files/multimedia/pdfs/publication/allergy-labelling-prepacked.pdf.

Gendel, S. M. (2012). Comparison of international food allergen labeling regulations. Regulatory Toxicology and Pharmacology, 63(2), 279-285.

Gendel, S. M. (2013). The Regulatory Challenge of Food Allergens. Journal of Agricultural Food Chemistry, 61, 5634-5637.

Grimshaw, K. E. C., et al. (2014). Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data. Allergy, 133(2), 511-519.

Haddeland, U., et al. (2005). Putative regulatory T cells are impaired in cord blood from neonates with hereditary allergy risk. Pedriatr Allergy Immunol., 16, 104-112.

Hirst, B. (2014). Survey of Allergen Advisory Labelling and Allergen Content of UK Retail Pre-Packed Processed Foods. Reading Scientific Services Ltd. https://www.food.gov.uk/science/research/allergy-research/fs241038.

Jackson, W. F. (2003). Food Alergy. 2003. http://ilsi.eu/wp-content/uploads/sites/3/2016/06/C2003Food_All.pdf.

Jones, S. M., Burks, A. W., & Dupont, C. (2014). tate of the art on food allergen immunotherapy: Oral, sublingual, and epicutaneous. American Academy of Allergy, Asthma & Immunology. 2014. http://dx.doi.org/10.1016/j.jaci.2013.12.

Lanser, B. J., Wright, B. L., Orgel, K. A., Vickery, B. P., & Fleischer, D. M. (2015). Current Options for the Treatment of Food Allergy. Pediatr Clin., 62, 1531-1549.

Lee, B. W., Pei-Chi Shek, L., Gerez, I. F. A., Soh, S. E., & Van Bever, H. P. (2008). Food Allergy - Lessons from Asia. World Allergy Organ J., 1(7), 129-133.

Marins, B. R., Araujo, I. S., & Jacob, S. C. (2014). Vigilância Sanitária e direito à comunicação: a rotulagem de alimentos como espaço de cidadania. Vig Sanit Debate, 2(4), 86-95.

Martino, D. J., & Prescott, S. L. (2010). Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy, 65, 7-15.

Mcbride, D., et al. (2012). The EuroPrevall birth cohort study on food allergy: baseline characteristics of 12,000 newborns and their families from nine European countries. Pediatr Allergy Immunol, 23, 230-239.

Mercosul (2015 a). Mercosur/SGT Nº 3/Acta Nº 04/15 LVII Reunión Ordinaria del Subgrupo de Trabajo Nº 3 “Reglamentos Técnicos y Evaluación de La Conformidad”. http://www.puntofocal.gov.ar/doc/lvii_ac_04-15_acta.pdf

Mercosul (2015 b). Mercosur/GMC/Acta Nº 02/15 XLVI Reunión Extraordinaria Del Grupo Mercado Común. http://www.puntofocal.gov.ar/doc/gmc_ex02-15.pdf

Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. (2014). Guia alimentar para a população brasileira. (2a ed.), 1. reimpr. Brasília: Ministério da Saúde, 156 p.

Ministerio de la Salud Pública y Bienertar Social. (2018). Resolución S.G. n° 402. https://www.inan.gov.py/site/?p=1212

Neu, J., & Rushing, J. (2011). Cesarean Versus Vaginal Delivery: Long-term Infant Outcomes and the Hygiene Hypothesis. Clinics in perinatology, 38(2), 321-331.

Odijk, J., et al. (2003). Breastfeeding and allergic disease: a multidisciplinary review of the literature (1966–2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy, 58, 833-843.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.

Pieretti, M. M., et al. (2009). Audit of manufactured products: Use of allergen advisorylabels and identification of labeling ambiguities. J Allergy Clin Immunol., 124(2), 337-341.

República Oriental del Uruguay (2020). Proyecto para declaración de alérgenos y sustancias que producen reacciones adversas en los rótulos de los alimentos, cualquiera sea su origen, envasados en ausencia del cliente, listos para ser ofrecidos al consumidor (dec. 117/006 del RBN). https://www.gub.uy/ministerio-salud-publica/sites/ministerio-salud-publica/files/2020-09/PROYECTO%20DE%20AL%C3%89RGENOS%20Y%20SUSTANCIAS%20ADVERSAS%20P ARA%20CONSULTA%20P%C3%9ABLICA.pdf.

Santos, A. L. S. β-lactoglobulina em biscoitos semidoces: estudo de degradação no processamento e potencial antigênico, validação de método e avaliação da rotulagem. [Dissertação de Mestrado do Programa de Pós-graduação em Ciência de Alimentos da Universidade Federal de Minas Gerais]. Belo Horizonte: UFMG. https://repositorio.ufmg.br/handle/1843/BUBD-AMUSAB.

Santos, P. P. B. Estudo da degradação e potencial antigênico de proteínas do ovo no processamento de biscoitos semidoces e validação de método imunoenzimático. [Dissertação de Mestrado do Programa de Pós-graduação em Ciência de Alimentos da Universidade Federal de Minas Gerais]. Belo Horizonte: UFMG. https://repositorio.ufmg.br/handle/1843/BUOS-BATFN3

Secretaría de Políticas, Regulación e Institutos, Secretaría De Agregado De Valor. (2017). Resolución Conjunta 11-E/2017. https://www.argentina.gob.ar/normativa/nacional/resoluci%C3%B3n-11-2017-280582/texto

Sicherer, S. H. (2011). Epidemiology of food allergy. The Journal of Allergy and Clinical Immunology, 127(3), 594-602.

Sicherer, S. H., Sampson, H. A. (2018). Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. The Journal of Allergy and Clinical Immunology, 141(1), 45-58.

Solé, D., et al. (2008). Consenso Brasileiro sobre alergia alimentar: 2007. Revista Brasileira de Alergia e Imunopatologia, 31(2), 64-89.

Zurzolo, G. A., et al. (2013). Precautionary allergen labelling following new labelling practice in Australia. Journal of Paediatrics and Child Health, 49, E306-E310.

Zurzolo, G. A., et al. (2016). Is advising food allergic patients to avoid food with precautionary allergen labelling out of date? Curr Opin Allergy Clin Immunol., 16(3), 272-277.

Published

03/01/2021

How to Cite

PALHARES, M. de P. P. e .; SANTOS, P. P. B. dos; SANTOS, A. L. S. dos .; GODDARD, C. L. .; SOUZA, S. V. C. de. Allergenic foods from a regulatory perspective: a review. Research, Society and Development, [S. l.], v. 10, n. 1, p. e7310111541, 2021. DOI: 10.33448/rsd-v10i1.11541. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/11541. Acesso em: 16 apr. 2024.

Issue

Section

Agrarian and Biological Sciences