Desafíos en el manejo del cáncer durante la pandemia de SARS-CoV-2: una revisión sistemática

Autores/as

DOI:

https://doi.org/10.33448/rsd-v10i3.13251

Palabras clave:

COVID-19; SARS-CoV-2; Cáncer; Oncología; Oncología quirúrgica.

Resumen

La propagación del SARS-CoV-2 y la instalación de una pandemia generaron cambios drásticos en el estilo de vida de la sociedad, en las prácticas de salud y en la forma en que hacemos y consumimos ciencia. Existen innumerables incertidumbres sobre el virus y sus implicaciones para la salud, especialmente para las personas de grupos vulnerables, como los pacientes oncológicos. El objetivo de esta revisión sistemática fue identificar cuál ha sido la realidad de la oncología en la pandemia del SARS-CoV-2. Se realizó una revisión sistemática en la plataforma Pubmed®, basada en el protocolo Prisma, mediante la búsqueda de las siguientes palabras clave: COVID-19 y Cancer. De los 94 trabajos seleccionados, entre revisiones sistemáticas, revisiones, ensayos aleatorizados, estudios multicéntricos, metaanálisis, ensayos clínicos controlados, estudios comparativos e informes de casos, solo 36 publicaciones correspondieron al propósito de este estudio y fueron utilizadas. Los resultados mostraron que, a pesar del gran volumen de estudios, no existe un consenso sobre las medidas estándar de oro. Dado que las personas con cáncer tienden a evolucionar con condiciones más graves cuando se infectan con SARS-CoV-2, los servicios de oncología han adoptado protocolos para garantizar un manejo adecuado y prevenir la propagación de la infección a sus instalaciones. La posible escasez de recursos durante la pandemia de SARS-CoV-2 trajo la necesidad de adaptar la conducta clínica en oncología. Teniendo en cuenta la gravedad y la posibilidad de una progresión brusca de algunos tipos de cáncer, los profesionales deben analizar todos los casos de forma individual para determinar el mejor abordaje.

Citas

Ackermann, M., Verleden, S. E., Kuehnel, M., Haverich, A., Welte, T., Laenger, F., Vanstapel, A., Werlein, C., Stark, H., Tzankov, A., Li, W. W., Li, V. W., Mentzer, S.J. & Jonigk, D. (2020). Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19. New England Journal of Medicine. DOI: 10.1056/NEJMoa2015432.

Al‐Shamsi, H. O., Alhazzani, W., Alhuraiji, A., Coomes, E. A., Chemaly, R. F., Almuhanna, M., Wolff, R. A., Ibrahim, N.K., Chua, M. L. K., Hotte, S. J., Meyers, B. M., Elfiki, T., Curigliano, G., Eng, C., Grothey, A. & Xie, C. (2020). A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID‐19) pandemic: an international collaborative group. The oncologist, 25(6), e936. DOI: 10.1634/theoncologist.2020-0213.

Albano, D., Bertagna, F., Bertoli, M., Bosio, G., Lucchini, S., Motta, F., Panarotto, M. B., Peli, A., Camoni, L., Bengel, F. M. & Giubbini, R. (2020). Incidental findings suggestive of COVID-19 in asymptomatic patients undergoing nuclear medicine procedures in a high-prevalence region. Journal of Nuclear Medicine, 61(5), 632-636. DOI: 10.2967/jnumed.120.246256.

Ardura, M., Hartley, D., Dandoy, C., Lehmann, L., Jaglowski, S., & Auletta, J. J. (2020). Addressing the impact of the Coronavirus Disease (COVID-19) pandemic on hematopoietic cell transplantation: Learning networks as means for sharing best practices. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.018.

Bachanova, V., Bishop, M. R., Dahi, P., Dholaria, B., Grupp, S. A., Hayes-Lattin, B., Janakiram, M., Maziarz, R. T., McGuirk, J. P., Nastoupil, L. J., Oluwole, O. O., Perales, M-A., Porter, D. L. & Riedell, P. A. (2020). CAR T Cell Therapy During the COVID-19 Pandemic. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.008.

Banna, G., Curioni-Fontecedro, A., Friedlaender, A., & Addeo, A. (2020). How we treat patients with lung cancer during the SARS-CoV-2 pandemic: primum non nocere. ESMO open, 4(Suppl 2), e000765. DOI:10.1136/ esmoopen-2020-000765.

Ciliberto, G., Mancini, R., & Paggi, M. G. (2020). Drug repurposing against COVID-19: focus on anticancer agents. Journal of Experimental & Clinical Cancer Research, 39, 1-9. DOI: 10.1186/s13046-020-01590-2.

Combs, S. E., Belka, C., Niyazi, M., Corradini, S., Pigorsch, S., Wilkens, J., Grosu, A. L., Guckenberger, M., Ganswindt, U. & Bernhardt, D. (2020). First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments. Radiation Oncology, 15, 1-12. DOI: 10.1186/s13014-020-01527-1.

Cucinotta, D., & Vanelli, M. (2020). WHO declares COVID-19 a pandemic. Acta bio-medica: Atenei Parmensis, 91(1), 157-160. DOI: 10.23750/abm.v91i1.9397.

Dariya, B., & Nagaraju, G. P. (2020). Understanding novel COVID-19: Its impact on organ failure and risk assessment for diabetic and cancer patients. Cytokine & Growth Factor Reviews. DOI: 10.1016/j.cytogfr.2020.05.001.

de la Viña, J. I., & Mayol, J., & Ortega, A. L., & Navarrete, B. A. (2020). Lung cancer patients on the waiting list in the midst of the COVID-19 crisis: what do we do now? Archivos de bronconeumologia. DOI: 10.1016/j.arbr.2020.05.003.

Deo, S., Kumar, S., Kumar, N., Saikia, J., Bhoriwal, S., Bhatnagar, S., & Sharma, A. (2020). Guiding Principles for Cancer Surgery during the COVID-19 Pandemic. Indian Journal of Surgical Oncology, 1. DOI: 10.1007/s13193-020-01082-x.

SILVA FILHO, P. S. da P.; COSTA, R. E. A. R. da; SANTOS, M. B. L. dos; LIMA, S. P. N.; SILVA, L. de A. da; FREITAS, A. S.; SILVA, J. P. da; ARAÚJO, L. K. C. de; CUNHA, S. H.; ARAÚJO, F. W. C.; SILVA, A. P. A. da; ALVES, D. R. C. F.; MENDES, A. M.; LEÃO, C. de A.; KIRCHESCH, C. L.; MACEDO, J. L. (2020). Management of patients with cancer during the COVID-19 pandemic. Research, Society and Development, 9 (7), p. e628974609, 2020. DOI: 10.33448/rsd-v9i7.4609.

Gandhi, R. T., Lynch, J. B., & del Rio, C. (2020). Mild or moderate COVID-19. New England Journal of Medicine. DOI: 10.1056/NEJMcp2009249.

Glehen, O., Kepenekian, V., Bouché, O., Gladieff, L., & Honore, C. (2020). Treatment of primary and metastatic peritoneal tumors in the Covid-19 pandemic. Journal of Visceral Surgery. DOI: 10.1016/j.jviscsurg.2020.04.013.

Gosain, R., Abdou, Y., Singh, A., Rana, N., Puzanov, I., & Ernstoff, M. S. (2020). COVID-19 and cancer: a comprehensive review. Current Oncology Reports, 22(5). DOI: 10.1007/s11912-020-00934-7.

Guo, Y.-R., Cao, Q.-D., Hong, Z.-S., Tan, Y.-Y., Chen, S.-D., Jin, H.-J., Tan, K-S., Wang, D-Y. & Yan, Y. (2020). The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Medical Research, 7(1), 1-10. DOI: 10.1186/s40779-020-00240-0.

Huang, Z., Yan, J., Jin, T., Huang, X., Zeng, G., Adashek, M. L., Wang, X., Li, J., Zhou, D. & Wu, Z. (2020). The Challenges Of Urgent Radical Sigmoid Colorectal Cancer Resection In A COVID-19 Patient; A Case Report. International Journal of Surgery Case Reports. DOI: 10.1016/j.ijscr.2020.04.088.

Ierardi, A. M., Wood, B. J., Gaudino, C., Angileri, S. A., Jones, E. C., Hausegger, K., & Carrafiello, G. (2020). How to Handle a COVID-19 Patient in the Angiographic Suite. Cardiovascular and Interventional Radiology, 1-7. DOI: 10.1007/s00270-020-02476-8.

Jin, X.-H., Zheng, K. I., Pan, K.-H., Xie, Y.P., & Zheng, M.-H. (2020). COVID-19 in a patient with chronic lymphocytic leukaemia. The Lancet Haematology, 7(4), e351-e352. DOI: 10.1016/S2352-3026(20)30074-0.

Kimmig, R., Verheijen, R. H., & Rudnicki, M. (2020). Robot assisted surgery during the COVID-19 pandemic, especially for gynecological cancer: a statement of the Society of European Robotic Gynaecological Surgery (SERGS). Journal of Gynecologic Oncology, 31(3). DOI: 10.3802/jgo.2020.31.e59.

Ky, B., & Mann, D. L. (2020). COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities. JACC: Basic to Translational Science, 5(5), 501-517. DOI: 10.1016/j.jacbts.2020.04.003.

Ljungman, P., Mikulska, M., de la Camara, R., Basak, G. W., Chabannon, C., Corbacioglu, S., Duarte, R., Dolstra, H., Lankester, A. C., Mohty, M., Montoto, S., Murray, J., de Latour, R. P., Snowden, J. A., Yakoub-Agha, I., Verhoeven, B., Kröger, N. & Styczynski, J. (2020). The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy. Bone marrow transplantation, 1-6. DOI: 10.1038/s41409-020-0919-0.

Mahmoudjafari, Z., Alexander, M., Roddy, J., Shaw, R., Shigle, T. L., Timlin, C., & Culos, K. (2020). American Society for Transplantation and Cellular Therapy Pharmacy Special Interest Group Position Statement on Pharmacy Practice Management and Clinical Management for COVID-19 in Hematopoietic Cell Transplant and Cellular Therapy Patients in the United States. Biology of Blood and Marrow Transplantation. DOI: 10.1016/j.bbmt.2020.04.005.

Minotti, C., Tirelli, F., Barbieri, E., Giaquinto, C., & Donà, D. (2020). How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection? A systematic review. Journal of Infection. DOI: 10.1016/j.jinf.2020.04.026.

Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P. & Stewart, L. A. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Systematic reviews, 4(1), 1. DOI: 10.1186/2046-4053-4-1.

Moujaess, E., Kourie, H. R., & Ghosn, M. (2020). Cancer patients and research during COVID-19 pandemic: a systematic review of current evidence. Critical Reviews in Oncology/Hematology, 102972. DOI: 10.1016/j.critrevonc.2020.102972.

Nannan, Z., Jie, S., Lizhong, Z., & Shuanying, Y. (2020). Clinical Characteristics and Coping Strategies of Neoplasms with 2019 Novel Coronavirus Infection. Chinese Journal of Lung Cancer, 23(4). DOI: 10.3779/j.issn.1009-3419.2020.102.15.

Paul, S., Rausch, C. R., Jain, N., Kadia, T., Ravandi, F., DiNardo, C. D., Welch, M. A., Dabaja, B. S., Daver, N., Garcia-Manero, G., Wierda, W., Pemmaraju, N., Bravo, G. M., Thompson, P., Verstovsek, S., Konopleva, M., Kantarjian, H. & Jabbour, E. (2020). Treating Leukemia in the Time of COVID-19. Acta Haematologica, 1-13. DOI: 10.1159/000508199.

Pawar, T., Pokharkar, A., Gori, J., Pandey, D., Rohila, J., Dsouza, A., & Saklani, A. (2020). The Technique and Justification for Minimally Invasive Surgery in COVID-19 Pandemic: Laparoscopic Anterior Resection for Near Obstructed Rectal Carcinoma. Journal of Laparoendoscopic & Advanced Surgical Techniques, 30(5), 485-487. DOI: 10.1089/lap.2020.0241.

Pimentel, B. (2020). As disfunções olfativas e gustativas como apresentação clínica da COVID-19. Research, Society and Development, 9 (8), e64985072. DOI: http://dx.doi.org/10.33448/rsd-v9i8.5072.

Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da Pesquisa Científica. [e-book]. (1ª ed). Santa Maria: UAB/NTE/UFSM. Retrieved from: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa -Cientifica.pdf?sequence=1. Access in: 04 mar. 2021.

Puliatti, S., Eissa, A., Eissa, R., Amato, M., Mazzone, E., Dell’Oglio, P., Sighinolfi, M. C., Zoeir, A., Micali, S., Bianchi, G., Patel, V., Wiklund, P., Coelho, R. F., Bernhard, J-C., Dasgupta, P., Mottrie, A. & Rocco, B. (2020). COVID‐19 and urology: A comprehensive review of the literature. BJU international. DOI: 10.1111/bju.15071.

Shinde, R. S., Naik, M. D., Shinde, S. R., Bhandare, M. S., Chaudhari, V. A., Shrikhande, S. V., & Dcruz, A. K. (2020). To Do or Not to Do?—A Review of Cancer Surgery Triage Guidelines in COVID-19 Pandemic. Indian Journal of Surgical Oncology, 1. DOI: 10.1007/s13193-020-01086-7.

Spezzani, V., Piunno, A., & Iselin, H.-U. (2020). Benign COVID-19 in an immunocompromised cancer patient-the case of a married couple. Swiss Medical Weekly, 150(1516). DOI: 10.4414/smw.2020.20246.

Tchelebi, L. T., Haustermans, K., Scorsetti, M., Hosni, A., Huguet, F., Hawkins, M. A., Dawson, L. A. & Goodman, K. A. (2020). Recommendations on the use of radiation therapy in managing patients with gastrointestinal malignancies in the era of COVID-19. Radiotherapy and Oncology. DOI: 10.1016/j.radonc.2020.04.010.

Tian, S., Hu, W., Niu, L., Liu, H., Xu, H., & Xiao, S.-Y. (2020). Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer. Journal of Thoracic Oncology. DOI: 10.1016/j.jtho.2020.02.010.

van de Haar, J., Hoes, L. R., Coles, C. E., Seamon, K., Fröhling, S., Jäger, D., Valenza, F., de Braud, F., de Petris, L., Bergh, J., Ernberg, I., Besse, B., Barlesi, F., Garralda, E., Piris-Giménez, A., Baumann, M., Apolone, G., Soria, J. C., Tabernero, J., Caldas, C. & Voest, E. E. (2020). Caring for patients with cancer in the COVID-19 era. Nature Medicine, 26(5), 665-671. DOI: 10.1038/s41591-020-0874-8.

von Lilienfeld-Toal, M., Vehreschild, J. J., Cornely, O., Pagano, L., Compagno, F., & Hirsch, H. H. (2020). Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases. Leukemia, 1-8. DOI: 10.1038/s41375-020-0832-y.

Wei, W., Zheng, D., Lei, Y., Wu, S., Verma, V., Liu, Y., Wei, X., Bi, J., Hu, D. & Han, G. (2020). Radiotherapy workflow and protection procedures during the Coronavirus Disease 2019 (COVID-19) outbreak: Experience of the Hubei Cancer Hospital in Wuhan, China. Radiotherapy and Oncology. DOI: 10.1016/j.radonc.2020.03.029.

Weisel, K. C., Morgner-Miehlke, A., Petersen, C., Fiedler, W., Block, A., Schafhausen, P., Knobloch, J. K. & Bokemeyer, C. (2020). Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg. Oncology Research and Treatment, 43(6), 307-313. DOI: 10.1159/000508272.

Weller, M., & Preusser, M. (2020). How we treat patients with brain tumour during the COVID-19 pandemic. ESMO open, 4(Suppl 2), e000789. DOI: 10.1136/esmoopen-2020-000789.

World Health Organization (2020). Rolling updates on coronavirus disease (COVID-19). Retrieved from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/events-as-they-happen.

Ye, Z., Hong, Y., Wu, X., Hong, D., Zhang, Y., Dong, X., Rao, Y. & Lu, X. (2020). Management of a colon cancer patient infected with corona virus disease 2019. Journal of Zhejiang University (Medical Science), 49(1), 0-0. DOI: 10.3785/j.issn.1008-9292.2020.03.12.

Yeo, C., Kaushal, S., & Yeo, D. (2020). Enteric involvement of coronaviruses: is faecal–oral transmission of SARS-CoV-2 possible? The lancet Gastroenterology & hepatology, 5(4), 335-337. DOI: 10.1016/S2468-1253(20)30048-0.

Zhang, H., Xie, C., & Huang, Y. (2020c). Treatment and outcome of a patient with lung cancer infected with severe acute respiratory syndrome Coronavirus-2. Journal of Thoracic Oncology, 15(5), e63-e64. DOI: 10.1016/j.jtho.2020.02.025.

Zhang, L., Zhu, F., Xie, L., Wang, C., Wang, J., Chen, R., Jia, P., Guan, H. Q., Peng, L., Chen, Y., Peng, P., Zhang, P., Chu, Q., Shen, Q., Wang, Y., Xu, S.Y., Zhao, P. J., & Zhou, M. (2020a). Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China. Annals of Oncology. DOI: 10.1016/j.annonc.2020.03.296.

Zhang, X., Song, K., Tong, F., Fei, M., Fei, M., Guo, H., Lu, Z., Wang, J., & Zheng, C. (2020b). First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab. Blood advances, 4(7), 1307. DOI: 10.1182/bloodadvances.2020001907.

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14/03/2021

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OLIVEIRA, A. P. A. .; SCHAFRANEK , A. R. de M. .; CARVALHO , L. de O. B. .; VITRO , M. M. de .; FRAZÃO , R. M. .; NASCIMENTO , V. A. .; OLIVEIRA, P. F. de. Desafíos en el manejo del cáncer durante la pandemia de SARS-CoV-2: una revisión sistemática . Research, Society and Development, [S. l.], v. 10, n. 3, p. e25910313251, 2021. DOI: 10.33448/rsd-v10i3.13251. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13251. Acesso em: 26 nov. 2024.

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