Evidencia científica sobre la presencia de trastornos mentales derivados de la infección por SARS-CoV-2 en personas con COVID-19: scoping review
DOI:
https://doi.org/10.33448/rsd-v11i8.26562Palabras clave:
SARS-CoV-2; COVID-19; Desordenes mentales; Psicopatología.Resumen
Objetivos: Identificar evidencia científica sobre la presencia de trastornos mentales por infección por SARS-CoV-2 en personas diagnosticadas con COVID-19; identificar los tipos de trastornos mentales; describir la asociación fisiopatológica de la infección por SARS-CoV-2 con trastornos mentales; y describir las características de edad y sexo. Esta es una Scoping Review realizada en las bases de datos: MEDLINE/PubMed, CINAHL, Web of Science, BVS, Cochrane Library, SCOPUS, Embase, LILACS. Y en los siguientes sitios: Google Scholar, ProQuest Dissertations and Theses y Grey Literature. Se utilizaron los descriptores (comorbilidad O secuela O complicaciones) Y (Salud mental O Trastornos mentales O Enfermedad mental) Y (SARS-CoV-2 O COVID-19 O coronavirus). Los criterios de inclusión fueron: artículos que respondieran a la pregunta orientadora, disponibles en su totalidad, con diferentes enfoques metodológicos, en línea, en inglés, español y portugués. Se excluyeron: artículos sin libre acceso; cartas de opinión al editor; editoriales; y libros Fueron seleccionados diez estudios, que señalaron la alta prevalencia de ocurrencia de trastornos mentales en pacientes diagnosticados con COVID-19, su etiología es multifactorial, siendo atribuida al daño del proceso infeccioso y a los estresores, resultantes de la pandemia. Los trastornos encontrados fueron: trastornos de estrés; de humor; psicóticos; obsesivo compulsivo; de ansiedad y sueño-vigilia. Los de mayor prevalencia de afectación fueron la ansiedad y la depresión. No hubo diferencia significativa en cuanto a la prevalencia por sexo. La edad media de los participantes fue de 46,1 años. Por ello, es necesario conocer las posibles secuelas del COVID-19, para poder apoyar integralmente a esta población.
Citas
Almutairi, M. et al (2021). Neuroinflammation and Its Impact on the Pathogenesis of COVID-19. Front Med (Lausanne), 8: 745789. https://doi.org/10.3389/fmed.2021.745789
APA. American Psychiatric Association (2014). Manual diagnóstico e estatístico de transtornos mentais: DSM-5.
Banerjee, D. (2020). The impact of Covid-19 pandemic on elderly mental health. Inter. Journal of Geriatric Psychiatry. https://doi.org/10.1002/gps.5320.
Bastien, C. et al (2001). Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Med., 2: 297– 307. https://doi.org/10.1016/S1389-9457(00)00065-4.
Bo, H-X. et al (2021). Posttraumatic stress symptoms and attitude toward crisis mental health services among clinically stable patients with COVID-19 in China. Psychological Medicine, vol 5. https://doi.org/10.1017/S0033291720000999.
Bottemanne, H., et al (2021). SARS-CoV-2 Psychiatric Sequelae: An Urgent Need of Prevention. Front Psychiatry, 9,12:738696. https://doi.org/10.3389/fpsyt.2021.738696.
Brooks, S., et al (2020). The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet, 395:912–20. 2020. https://doi.org/10.1016/S0140-6736(20)30460-8.
Casagrande, M., et al (2020). The enemy who sealed the world: effects quarantine due to the COVID-19 on sleep quality, anxiety, and psychological distress in the Italian population. Sleep Med., 75:12-20. https://doi.org/10.1016/j.sleep.2020.05.011.
Cai, X., et al (2020). Psychological Distress and Its Correlates Among COVID-19 Survivors During Early Convalescence Across Age Groups. Am J Geriatr Psychiatry,28(10):1030-1039. https://doi.org/10.1016/j.jagp.2020.07.003.
Cevik, M., et al (2020). Virology, transmission, and pathogenesis of SARS-CoV-2. BMJ. https://doi.org/10.1136/bmj.m3862
Centers for Disease Control and Prevention (2021a). About COVID-19. www.cdc.gov.
Centers for Disease Control and Prevention (2021b). Symptons. www.cdc.gov.
Chen, J., (2020). Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viroses. Microbes and Infection, 22. https://doi.org/10.1016/j.micinf.2020.01.004.
Deng, J., et al (2021). The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis. Ann N Y Acad Sci.,1486(1):90-111. 2021. https://doi.org/10.1111/nyas.14506.
Desai, S., et al (2021). New-Onset Psychosis Following COVID-19 Infection. Cureus, 13(9):e17904. 10.7759/cureus.17904
Ferrando, S., et al (2020). COVID-19 Psychosis: A Potential New Neuropsychiatric Condition Triggered by Novel Coronavirus Infection and the Inflammatory Response? Psychosomatics, 61(5):551-555. https://doi.org/10.1016/j.psym.2020.05.012Get.
Galvão, T. F., Pansani, T. S. A. & Harrad, D. (2015). Principais itens para relatar Revisões sistemáticas e Meta-análises: A recomendação PRISMA*. Epidemiol. Serv. Saúde, 24(2): abr-jun. https://doi.org/10.5123/S1679-49742015000200017.
Generoso, J., et al (2021). Neurobiology of COVID-19: how can the virus affect the brain? Braz J Psychiatry., 43(6): 650–664.https://doi.org/10.1590/1516-4446-2020-1488.
Guo, Q., et al (2020). Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: A mixed-method study. Brain Behav Immun, 88:17-27. https://doi.org/10.1016/j.bbi.2020.05.038.
Hu, Y., et al (2020). Factors related to mental health of inpatients with COVID-19 in Wuhan, China. Brain Behav Immun.,89:587-593. https://doi.org/10.1016/j.bbi.2020.07.016.
Janiri, D., et al (2021). Posttraumatic Stress Disorder in Patients After Severe COVID-19 Infection. JAMA Psychiatry, 78(5):567-569. 10.1001/jamapsychiatry.2021.0109
Jha, N, et al (2021). Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations. J Mol Neurosci.,71(11):2192-2209. 10.1007/s12031-020-01767-6
Kar, S., et al (2020). Mental illnesses among COVID-19 patients: Possible immunological underpinnings. Asian J Psychiatr., 53: 102376.10.1016/j.ajp.2020.102376.
Khademil, M., et al (2021). Prevalence of Mental Health Problems and Its Associated Factors Among Recovered COVID-19 Patients During the Pandemic: A Single-Center Study. Front. Psychiatry. https://doi.org/10.3389/fpsyt.2021.602244.
Khan, S., et al (2021). Mental health consequences of infections by coronaviruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Brain Behav., 11(2):e01901. https://doi.org/10.1002/brb3.1901.
Kong, X., et al (2020). Prevalence and Factors Associated with Depression and Anxiety of Hospitalized Patients with COVID-19. MedRxiv and bioRxiv. https://doi.org/10.1101/2020.03.24.20043075
Kong, X, et al (2020). Effect of Psychological–Behavioral Intervention on the Depression and Anxiety of COVID-19 Patients. Front. Psychiatry. https://doi.org/10.3389/fpsyt.2020.586355.
Kroenke, K., et al (2001). PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9). https://doi.org/10.1046/j.1525-1497.2001.016009606.x.
Lai, J., et al (2020). Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019. JAMA Netw Open, 3(3):e203976. 10.1001/jamanetworkopen.2020.3976.
Lakhan, R., et al (2020). Prevalence of Depression, Anxiety, and Stress during COVID-19 Pandemic. J Neurosci Rural Pract., 11(4):519-525. 10.1055/s-0040-1716442
Lee, A, et al (2007). Stress and psychological distress among SARS survivors 1 year after the outbreak. Can J Psychiatry, 52(4):233-40. 10.1177/070674370705200405
Li, Y-C., et al (2020). The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol., 92(6):552-555. 10.1002/jmv.25728
Lima, A. A., et al. (2021). Characteristics of SARS-cov-2 aerosol dispersion in indoor air: scoping review. Research, Society and Development, 10(4), e44310414300. http://dx.doi.org/10.33448/rsd-v10i4.14300.)
Liu, X., et al (2021). Public mental health problems during COVID-19 pandemic: a large-scale meta-analysis of the evidence. Transl Psychiatry,384. https://doi.org/10.1038/s41398-021-01501-9.
Mascarello, K., et al (2021). Hospitalização e morte por COVID-19 e sua relação com determinantes sociais da saúde e morbidades no Espírito Santo: um estudo transversal. Epidemiol. Serv. Saude, 30(3):e2020919. 10.1590/S1679-49742021000300004.
Moreira, J. L., et al (2021). The psychiatric and neuropsychiatric repercussions associated with severe infections of COVID-19 and other coronaviruses. Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 106. https://doi.org/10.1016/j.pnpbp.2020.110159.
Morettin, P, & Singer, Julio (2021). Estatística e Ciência de Dados. Departamento de Estatística Universidade de São Paulo.
Morin, C., et al (2021). Insomnia, anxiety, and depression during the COVID-19 pandemic: an international collaborative study. Sleep Medicine, vol. 87. https://doi.org/10.1016/j.sleep.2021.07.035
Nakamura, Z., et al (2021). Neuropsychiatric Complications of COVID-19. Curr Psychiatry Rep.,16,23(5):25. 10.1007/s11920-021-01237-9
Napoleão, R. N., et al (2021). COVID-19: Compreendendo a “tempestade de citocinas”. Research, Society and Development, v. 10, n.5, e43710515150. 10.33448/rsd-v10i5.15150.
Organização Pan-Americana de Saúde (2020). Histórico da pandemia de COVID-19. https://www.paho.org/pt/covid19/historico-da-pandemia-covid-19.
Organização Pan-Americana de Saúde (2021). Coronavírus. https://www.paho.org/pt/topicos/coronavírus.
Ornell, F., et al (2020). “Pandemic fear” and COVID-19: mental health burden and strategies. Braz J Psychiatry. http://dx.doi.org/10.1590/1516-4446-2020-0008.
Pallanti, S., et al (2021). Neurocovid-19: A clinical neuroscience-based approach to reduce SARS-CoV-2 related mental health sequelae. J Psychiatr Res.,130:215-217. 10.1016/j.jpsychires.2020.08.008.
Parra, A. et al (2020). Psychotic symptoms in COVID-19 patients. A retrospective descriptive study. Psychiatry Res, 291:113254. 10.1016/j.psychres.2020.113254.
Peters, M. D. J. et al. (202). Chapter 11: Scoping Reviews (2020 version). JBI Manual for Evidence Synthesis.
Purssell, E., et al (2020). Impact of isolation on hospitalised patients who are infectious: systematic review with meta-analysis. BMJ Open, 18,10(2):e030371. 10.1136/bmjopen-2019-030371.
Qi, R., et al (2020). Psychological morbidities and fatigue in patients with confirmed COVID-19 during disease outbreak: prevalence and associated biopsychosocial risk factors. MedRxiv and bioRxiv. https://doi.org/10.1101/2020.05.08.20031666.
Raijkumar, R. (2020b). Contamination and infection: What the coronavirus pandemic could reveal about the evolutionary origins of obsessive-compulsive disorder. Psychiatry Research., 289. https://doi.org/10.1016/j.psychres.2020.113062.
Raijkumar, R. (2020a). COVID-19 and mental health: A review of the existing literature. Asian Journal of Psychiatry, 52. https://doi.org/10.1016/j.ajp.2020.102066.
Resende, M., et al (2015). O DSM-5 e suas implicações no processo de medicalização da existência. Psicol. rev., 21(3), 534-546. 2015. http://dx.doi.org/DOI-10.5752/P.1678-9523.2015v21n3p534.
Rogers, J., et al (2021). Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic. Lancet Psychiatry, 7:611. https://doi.org/10.1016/S2215-0366(20)30203-0
Sadeghi, M., et al (2016). Validity and Reliability of Persian Version of “Post-Traumatic Stress Disorder Scale” in War Veterans. Iran J War Public Health, 8:243–9. https://ijwph.ir/article-1-596-en.html.
Shafran, R, et al (2020). Recognising and addressing the impact of COVID-19 on obsessive-compulsive disorder. Lancet Psychiatry, 7(7):570-572. 10.1016/S2215-0366(20)30222-4.
Shi, L. et al (2020). Prevalence of and Risk Factors Associated With Mental Health Symptoms Among the General Population in China During the Coronavirus Disease 2019 Pandemic. JAMA Netw Open., 3(7):e2014053. 10.1001/jamanetworkopen.2020.14053
Shin, L., & Liberzon, I. (2010). The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology, 35:169-91. https://www.nature.com/articles/npp200983
Spitzer, R., et al (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch. Intern. Med., 166. 10.1001/archinte.166.10.1092.
Taquet, M. et al (2021). 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records. Lancet Psychiatry, 8: 416–27. https://doi.org/10.1016/S2215-0366(21)00084-5.
Uher, R, & Zwicker, A. (2017). Etiology in psychiatry: embracing the reality of poly‐gene‐environmental causation of mental illness. World Psychiatry, 16(2):121-129. https://doi.org/10.1002/wps.20436
World Health Organization (2021a). Mental health & COVID-19. www.who.in. https://www.who.int/teams/mental-health-and-substance-use/mental-health-and-covid-19.
World Health Organization (2021b). WHO Coronavirus (COVID-19) Dashboard. https://covid19.who.int.
Wu, T., et al (2021). Prevalence of mental health problems during the COVID-19 pandemic: A systematic review and meta-analysis. J Affect Disord, 281:91-98. https://doi.org/10.1016/j.jad.2020.11.117.
Xia, H. & Lazartigues, E. (2008). Angiotensin-converting enzyme 2 in the brain: properties and future directions. J Neurochem. 2008. 10.1111/j.1471-4159.2008. 05723.x.
Yadav, R. et al (2021). Assessment of Depression, Anxiety, and Sleep Disturbance in COVID-19 Patients at Tertiary Care Center of North India. J Neurosci Rural Pract., 12(2):316-322. 10.1055/s-0040-1722811.
Yachou, Y., et al (2020). Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients. Neurol Sci.,41(10):2657-2669. 10.1007/s10072-020-04575-3.
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2022 Izabelly Carollynny Maciel Nunes; Verônica de Medeiros Alves; Anyele Albuquerque Lima; Alda Graciele Claudio dos Santos Almeida; Ana Paula Nogueira de Magalhães
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Los autores que publican en esta revista concuerdan con los siguientes términos:
1) Los autores mantienen los derechos de autor y conceden a la revista el derecho de primera publicación, con el trabajo simultáneamente licenciado bajo la Licencia Creative Commons Attribution que permite el compartir el trabajo con reconocimiento de la autoría y publicación inicial en esta revista.
2) Los autores tienen autorización para asumir contratos adicionales por separado, para distribución no exclusiva de la versión del trabajo publicada en esta revista (por ejemplo, publicar en repositorio institucional o como capítulo de libro), con reconocimiento de autoría y publicación inicial en esta revista.
3) Los autores tienen permiso y son estimulados a publicar y distribuir su trabajo en línea (por ejemplo, en repositorios institucionales o en su página personal) a cualquier punto antes o durante el proceso editorial, ya que esto puede generar cambios productivos, así como aumentar el impacto y la cita del trabajo publicado.