Kombucha: una revisión sistemática y un metanálisis de la evidencia experimental de sus efectos sobre la glucosa en sangre, la dislipidemia y el peso corporal en la diabetes mellitus

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Autores/as

DOI:

https://doi.org/10.33448/rsd-v11i6.29278

Palabras clave:

Revisión Sistemática; Diabetes mellitus; Bebidas azucaradas; Alimentos funcionales.

Resumen

La kombucha es una bebida a base de té fermentado sin alcohol producida por un cultivo simbiótico de bacterias y levaduras. Esta creciente popularidad en Estados Unidos y países desarrollados ha sido parte del movimiento de alimentos funcionales en el uso de infusiones de plantas como alternativa promisoria en los beneficios del microbioma en el tratamiento de la obesidad y la diabetes. Sin embargo, estudios recientes muestran informaciones controvertidas sobre los efectos de la Kombucha en la salud, muchas veces impulsada por diferentes teorías que conducen al uso empírico de la bebida sin estandarización de cantidad, formas y preparación, lo que puede causar daños a la salud humana. Dado eso, llevamos a cabo esta revisión sistemática para evaluar el efecto de Kombucha en la salud a través de estudios preclínicos con evidencia científica disponible en la literatura, para permitir futuros estudios en humanos.

Citas

Afsharmanesh, M. & Sadaghi, B. (2014). Effects of dietary alternatives (probiotic, green tea powder, and Kombucha tea) as antimicrobial growth promoters on growth, ileal nutrient digestibility, blood parameters, and immune response of broiler chickens. Comp. Clin. Path. 23(3):717–24

Alkhatib, A. & Atcheson, R. (2017). Yerba Maté (Ilex paraguariensis) Metabolic, Satiety, and Mood State Effects at Rest and during Prolonged Exercise. Nutrients. 9(8):

Alkhatib, A., Tsang, C., Tiss, A., Bahorun, T., Arefanian, H., et al. (2017). Functional foods and lifestyle approaches for diabetes prevention and management. Nutrients. 9(12):

Amarasinghe, H., Weerakkody, N.S., & Waisundara, V.Y. (2018). Evaluation of physicochemical properties and antioxidant activities of kombucha “Tea Fungus” during extended periods of fermentation. Food Sci. Nutr. 6(3):659–65

American Diabetes Association. (2014). Diagnosis and classification of diabetes mellitus. Diabetes Care. 37 Suppl 1:S81-90

Anagnostis, P., Katsiki, N., Adamidou, F., Athyros, V.G., Karagiannis, A., et al. (2013). 11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders? Metab. Clin. Exp. 62(1):21–33

Ansari, F., Pourjafar, H., Kangari, A., & Homayouni, A. (2019). Evaluation of the glucuronic acid production and antibacterial properties of kombucha black tea. Curr. Pharm. Biotechnol. 20(11):985–90

Bhattacharya, S., Gachhui, R., & Sil, P.C. (2013). Effect of Kombucha, a fermented black tea in attenuating oxidative stress mediated tissue damage in alloxan induced diabetic rats. Food Chem. Toxicol. 60:328–40

Buczkowska, E. O. & Jarosz-Chobot P. (2001). [Insulin effect on metabolism in skeletal muscles and the role of muscles in regulation of glucose homeostasis]. Prz. Lek. 58(7–8):782–87

Dashti, M. H. & Morshedi, A. (2000). A Comparison between The Effect of Black Tea and Kombucha Tea on Blood Glucose Level in Diabetic Rat. Medic Journal of Islamic World Academy of Sciences. 13(2):83–7

Dimidi, E., Cox, S.R., Rossi, M., & Whelan, K. (2019). Fermented foods: definitions and characteristics, impact on the gut microbiota and effects on gastrointestinal health and disease. Nutrients. 11(8):

Dimitriadis, G., Mitrou, P., Lambadiari, V., Maratou, E., & Raptis, S.A. (2011). Insulin effects in muscle and adipose tissue. Diabetes Res. Clin. Pract. 93 Suppl 1:S52-9

Ernst, E. (2003). Kombucha: a systematic review of the clinical evidence. Forsch Komplementarmed Klass Naturheilkd. 10(2):85–87

Grota A. J. de A..; Silva, D. C. da; Figueiredo, G. T. de O.; & Castro, R. da S.. (2021) Consultation and pharmaceutical diagnosis of Diabetes Mellitus type 2: a systematic review. Research, Society and Development, 10(14), e18110142208710.33448/rsd-v10i14.22087.

Hooijmans, C. R., Rovers, M. M., de Vries, R. B. M., Leenaars, M., Ritskes-Hoitinga, M., & Langendam, M. W. (2014). SYRCLE’s risk of bias tool for animal studies. BMC Med. Res. Methodol. 14:43

Hosseini, S.A., Gorjian, M., Rasouli, L., Shirali, S. (2015). A Comparison between the Effect of Green Tea and Kombucha Prepared from Green Tea on the Weight of Diabetic Rat. Biosci., Biotechnol. Res. Asia. 12(SEMAR):141–46

Hosseini, S.A., Rasouli, L., Gorjian, M., & Yadollahpour, A. (2016). A comparative study of the effect of Kombuchaprepared from green and black teas on the level of blood glucose and lipidprofile of diabetic rats. International Journal of Pharmaceutical Research and Allied Sciences. 5(2):93–102

Johnston, K.L., Clifford, M.N., & Morgan, L.M. (2003). Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am. J. Clin. Nutr. 78(4):728–33

Kapp, J.M. & Sumner, W. (2019). Kombucha: a systematic review of the empirical evidence of human health benefit. Ann. Epidemiol. 30:66–70

Marinho, F. P.; Loyola, I. S.; Monteiro, I. de O. F.; Castro, T. M.; Carvalho, M. das G. de S.; Garcia, J. A. D.; Sivério, A. C. P.; & Santos, G. B. Interrelationship between COVID-19 and diabetes mellitus: a systematic review. Research, Society and Development, 10(2), e4810212191, 10.33448/rsd-v10i2.12191.

Martínez Leal, J., Valenzuela Suárez, L., Jayabalan, R., Huerta Oros, J., & Escalante-Aburto, A. (2018). A review on health benefits of kombucha nutritional compounds and metabolites. CyTA - Journal of Food. 16(1):390–99

Matsui, T., Ogunwande, I.A., Abesundara, K.J.M., & Matsumoto, K. (2006). Anti-hyperglycemic Potential of Natural Products. Mini Rev. Med. Chem. 6(3):349–56

Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., & PRISMA Group. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Med. 6(7):e1000097

Morshedi, A., Dashti, M.H., Mosaddegh, M.H., Rafati, A., & Salami, A.S. (2006). The chronic effectof Kombucha Tea consumption on weight loss in diabetic rats. J Herbs Spices Med Plants. 5(2):17–22

Oliveira, J.E.P., Montenegro Junior, R.M., & Vencio, S. (2017). Diretrizes Da Sociedade Brasileira de Diabetes2017-2018

Rodríguez-Ramiro, I., Ramos, S., Bravo, L., Goya, L., & Martín, M.Á. (2011). Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway. J. Nutr. Biochem. 22(12):1186–94

Ruiz-Ramos, M., Escolar-Pujolar, A., Mayoral-Sánchez, E., Corral-San Laureano, F., & Fernández-Fernández, I. (2006). [Diabetes mellitus in Spain: death rates, prevalence, impact, costs and inequalities]. Gac. Sanit. 20 Suppl 1:15–24

R Core Team. (2018). A language and environment for staticalcomputing. R Foundation for Statical Computing. www.R-project.org.

Saklayen, M.G. (2018). The global epidemic of the metabolic syndrome. Curr. Hypertens. Rep. 20(2):12

Song, F., Eastwood, A.J., Gilbody, S., Duley, L., & Sutton, A.J. (2000). Publication and related biases. Health Technol. Assess. 4(10):1–115

Srihari, T., Karthikesan, K., Ashokkumar, N., & Satyanarayana, U. (2013). Antihyperglycaemic efficacy of kombucha in streptozotocin-induced rats. J. Funct. Foods. 5(4):1794–1802

Sterne, J.A.C., Hernan, M.A., McAleenan, A., Reeves, B.C., & Higgins, J.P.T. (2019). Chapter 25: assessing risk of bias in a non-randomized study. In Cochrane Handbook for Systematic Reviews of Interventions Version 6.0, eds. JPT Higgins, J Thomas, J Chandler, M Cumpston, T Li, et al. Hoboken: John Wiley & Sons

Tsang, C., Smail, N.F., Almoosawi, S., Davidson, I., & Al-Dujaili, E.A.S. (2012). Intake of polyphenol-rich pomegranate pure juice influences urinary glucocorticoids, blood pressure and homeostasis model assessment of insulin resistance in human volunteers. J. Nutr. Sci. 1:e9

Turner, R., Cull, C., & Holman, R. (1996). United Kingdom Prospective Diabetes Study 17: a 9-year update of a randomized, controlled trial on the effect of improved metabolic control on complications in non-insulin-dependent diabetes mellitus. Ann. Intern. Med. 124(1 Pt 2):136–45

Uțoiu, E., Matei, F., Toma, A., Diguță, C.F., Ștefan, L.M., et al. (2018). Bee Collected Pollen with Enhanced Health Benefits, Produced by Fermentation with a Kombucha Consortium. Nutrients. 10(10):

Viechtbauer, W. (2010). Conducting Meta-Analyses in R with the metafor Package. J. Stat. Softw. 36(3):

Yang, C.S., Wang, H., Li, G. X., Yang, Z., Guan, F. & Jin, H. (2011). Cancer prevention by tea: Evidence from laboratory studies. Pharmacol. Res. 64(2):113–22

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Publicado

05/05/2022

Cómo citar

MALLMANN, M. M. .; VALDERRAMAS, S. .; GARCIA, A. C. .; PETTERLE, R. R. .; DUARTE, M. L.; RAMOS JUNIOR, O. . Kombucha: una revisión sistemática y un metanálisis de la evidencia experimental de sus efectos sobre la glucosa en sangre, la dislipidemia y el peso corporal en la diabetes mellitus: ,. Research, Society and Development, [S. l.], v. 11, n. 6, p. e49011629278, 2022. DOI: 10.33448/rsd-v11i6.29278. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/29278. Acesso em: 22 nov. 2024.

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Sección

Ciencias de la salud