Posibles mecanismos fisiopatológicos de la disgeusia asociada a la infección por SARS-CoV-2 - Revisión de la Literatura

Autores/as

DOI:

https://doi.org/10.33448/rsd-v12i3.40424

Palabras clave:

Coronavirus; Disgeusia; Ageusia.

Resumen

Desde el comienzo de la pandemia de COVID-19 en diciembre de 2019, muchos pacientes infectados han notificado cambios en el gusto y el olfato como síntomas iniciales. El odontólogo debe ser capaz de diagnosticar este síntoma y remitir al paciente a servicios de salud especializados. Este estudio tuvo como objetivo realizar una revisión narrativa sobre la posible fisiopatología de la disgeusia y la ageusia en pacientes infectados por SARS-CoV-2. Los datos fueron recolectados de estudios identificados en las bases de datos de la BVS, Google Scholar, LILACS, PubMed, SciELO y Web of Science, utilizando como descriptores: disgeusia, ageusia, fisiopatología y coronavirus. Entre los posibles mecanismos de la disgeusia destacan la invasión viral al tejido nervioso, secundaria a alteraciones olfatorias, la relación con comorbilidades y fármacos, la asociación con la gran presencia del virus en saliva y su alta afinidad por varios receptores de la enzima angiotensina-2 presentes en la cavidad oral Por lo tanto, los cambios en el gusto son síntomas típicos en pacientes infectados con SARS-CoV-2 y que tienden a retroceder con el tiempo. Sin embargo, su fisiopatología, mecanismo de acción y pronóstico aún no están bien establecidos, lo que requiere más estudios experimentales.

Citas

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24/02/2023

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BUENO, M. V. . .; GALVÃO, G. S. .; NEVES, I. L. I.; SCHRÖTER, G. T.; MOREIRA, M. S. .; SANTOS-PAUL, M. A. dos .; CARVALHO, C. M. A. de .; NEVES, R. S.; MONTANO , T. C. P. Posibles mecanismos fisiopatológicos de la disgeusia asociada a la infección por SARS-CoV-2 - Revisión de la Literatura . Research, Society and Development, [S. l.], v. 12, n. 3, p. e6712340424, 2023. DOI: 10.33448/rsd-v12i3.40424. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/40424. Acesso em: 23 nov. 2024.

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Vol. 12 Núm. 3

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Derechos de autor 2023 Marcus Vinícius Bueno; Gustavo Souza Galvão; Itamara Lucia Itagiba Neves; Gabriella Torres Schröter; Maria Stella Moreira; Marcela Alves dos Santos-Paul; Cíntia Maria Alencar de Carvalho; Ricardo Simões Neves; Tânia Cristina Pedroso Montano

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