Terapia por fotobiomodulação: mecanismo de ação e importância clínica no tratamento da osteoartrite de joelho
DOI:
https://doi.org/10.33448/rsd-v10i1.12072Palavras-chave:
Osteoartrite; Laser; Reabilitação; Joelho.Resumo
A osteoartrite do joelho (OAJ) é uma das doenças articulares degenerativa progressiva mais comuns em todo o mundo e também uma das principais causas de incapacidade e danos à qualidade de vida. A terapia de fotobiomodulação (PBMT, do inglês Photobiomodulation Therapy) através de laser de baixa intensidade (LLLT, do inglês Low Level Laser Therapy) tem mostrado ser um tratamento promissora e com bons resultados para diversas doenças crônicas, incluindo as alterações que acometem o sistema articular. Dentro deste contexto, o objetivo deste estudo é proporcionar, por meio de uma revisão narrativa, uma compreensão das evidências atuais disponíveis sobre o mecanismo de ação e importância clínica da PBMT a laser no tratamento da OAJ. As buscas foram realizadas nas bases de dados bibliográficas do PubMed/MEDLINE, Biblioteca virtual da saúde (BVS), Web of Science e SciELO. Com base nos estudos revisados por pares, os dados laboratoriais em modelos animais experimentais e estudos clínicos mostram que a PBM é capaz de reduzir a morte de condrócitos, estimular a síntese de componentes da matriz extracelular (MEC), atenuar a liberação de mediadores inflamatórios e proteolíticos presente em doenças articulares crônicas, prevenindo assim a degradação do tecido articular e periarticulares. Consequentemente, clinicamente, pode ser observado melhora da dor, funcionalidade e qualidade de vida do indivíduo acometido com OAJ e tratados com a PBMT a laser. Assim, podemos concluir que a PBMT a laser pode constituir um excelente coadjuvante no tratamento da OAJ, uma vez que é um método não invasivo e também apresenta custos relativamente baixos.
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Copyright (c) 2021 Yuri Victor Barbosa Silva; Thiago Correia da Silva Rezzo; Carla Roberta Tim; Patrícia Gabrielli Vassão; Thalita Páez; Livia Assis Garcia
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