Eficácia antimicrobiana de associações medicamentosas com o hidróxido de cálcio na periodontite apical: Revisão sistemática
DOI:
https://doi.org/10.33448/rsd-v10i4.14593Palavras-chave:
Hidróxido de cálcio; Periodontite apical; Eficácia antibacteriana; Revisão sistemática.Resumo
O objetivo desta revisão sistemática foi comparar o desempenho clínico do hidróxido de cálcio (Ca(OH)2) como um medicamento intracanal sozinho ou combinado com agentes antimicrobianos. A pergunta do PICO era “A eficácia antibacteriana da pasta de hidróxido de cálcio como medicamento intracanal combinado com outras drogas é maior do que a da pasta de hidróxido de cálcio sozinha na periodontite apical?” O estudo foi realizado de acordo com as diretrizes PRISMA e registrado no PROSPERO (CRD42020205741). As pesquisas foram realizadas nas bases de dados PubMed / MEDLINE, Web of Science e Cochrane sem restrições de data de publicação. Inclusão: ensaios clínicos randomizados, estudos de intervenção não randomizados, estudos com mínimo de 10 pacientes, estudos comparando o uso de Ca(OH)2 sozinho e combinação com outros compostos, estudos avaliando dentes decíduos e permanentes com periodontite apical e estudos incluindo dentes não submetidos a retratamento. A ferramenta de risco de viés Cochrane para ensaios clínicos randomizados (RoB 2.0) foi usada para avaliar a validade interna dos estudos incluídos. Um total de 986 artigos foram recuperados e 12 ensaios clínicos randomizados selecionados, totalizando 499 pacientes incluídos nos estudos. A eficácia do Ca(OH)2 mais clorexidina foi semelhante ao Ca(OH)2 sozinho em oito artigos, enquanto um melhor efeito antibacteriano foi relatado em três estudos. A combinação com ciprofloxacino foi mais eficaz do que o uso de Ca(OH)2 sozinho no único estudo que testou esse antibiótico. Na periodontite apical assintomática, a eficácia da combinação de agentes antimicrobianos com Ca(OH)2 foi semelhante à do Ca (OH) 2 sozinho.
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Copyright (c) 2021 Christianne Velozo; Cleidiel Aparecido Araújo Lemos ; Diana Santana de Albuquerque; Belmiro Cavalcante do Egito Vasconcelos; Sandra Lúcia Dantas Moraes ; Eduardo Piza Pellizzer
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