A co-epidemia de Dengue e COVID-19 no Brasil: entre os desafios para o seu manejo e as consequências da desigualdade socioeconômica

Autores

DOI:

https://doi.org/10.33448/rsd-v10i5.14728

Palavras-chave:

COVID-19; Dengue; Arboviroses; Pandemia; Doenças tropicais negligenciadas.

Resumo

O SARS-CoV-2, agente etiológico da COVID-19, se espalhou pelo mundo, atingindo o status de pandemia em março de 2020. Neste cenário, as epidemias de dengue continuam a impactar os países endêmicos. Levando em consideração o aumento dos casos de dengue em todo o mundo, a pandemia de COVID-19 pode sinalizar um sério perigo para a saúde pública global. Em alguns países, a pandemia coincidiu com epidemias de dengue já instaladas. Assim, compreender os constituintes coletivos das arboviroses em tempos de pandemia é fundamental para uma análise significativa. O presente trabalho traz uma revisão narrativa elucidando impactos importantes decorrentes da co-epidemia e suas consequências em uma perspectiva mais ampla. Problemas com o diagnóstico diferencial dessas infecções são fatores agravantes para a decisão do manejo clínico e prognóstico dos indivíduos infectados. Além disso, as características socioeconômicas e etnia são fatores fundamentais tanto para a dinâmica de transmissão da dengue quanto para a COVID-19. Destaca-se também, um cenário que representa alto risco de colapso para os serviços de saúde no enfrentamento dos desafios para o combate e gestão de recursos. Conclui-se, portanto que, para superar a crise das epidemias simultâneas e suas graves consequências, devem ser considerados os aspectos históricos e sua relação com as condições de vulnerabilidade social, além da promoção ações específicas para o seu combate.

Referências

Apu, S. M. (2020). A double struggle: Home ministry PRO battling Covid-19, dengue. The Daily Star. https://www.thedailystar.net/coronavirus-deadly-new-threat/news/double-struggle-home-ministry-pro-battling-covid-19-dengue-1905013

Baqui, P., Bica, I., Marra, V., Ercole, A., & van der Schaar, M. (2020). Ethnic and regional variations in hospital mortality from COVID-19 in Brazil: a cross-sectional observational study. The Lancet Global Health, 8(8), e1018–e1026.

Bhatt, S., Gething, P. W., Brady, O. J., Messina, J. P., Farlow, A. W., Moyes, C. L., Drake, J. M., Brownstein, J. S., Hoen, A. G., Sankoh, O., Myers, M. F., George, D. B., Jaenisch, T., Wint, G. R. W., Simmons, C. P., Scott, T. W., Farrar, J. J., & Hay, S. I. (2013). The global distribution and burden of dengue. Nature, 496(7446), 504–507.

Braga, I. A., & Valle, D. (2007). Aedes aegypti: histórico do controle no Brasil* Aedes aegypti: History of Control in Brazil. Epidemiologia e Serviços de Saúde 2007, 16(2), 113–118.

Burkett-Cadena, N. D., & Vittor, A. Y. (2018). Deforestation and vector-borne disease: Forest conversion favors important mosquito vectors of human pathogens. Basic and Applied Ecology, 26, 101–110.

Burky, T. (2020). COVID-19 in Latin America. PubMed, January, 547–548.

Conasems, C. N. dos S. M. de S., & Conass, C. N. dos S. de S. (2020). Guia Orientador para o enfrentamento da pandemia Covid-19 na Rede de Atenção à Saúde. 89. https://www.conasems.org.br/guia-orienta-estados-e-municipios-para-o-enfrentamento-da-pandemia-de-covid-19-na-rede-de-atencao-a-saude/instrumento-orientador-conass-conasems-versao-final-3/

Cook, D. J., Mulrow, C. D., & Haynes, R. B. (1997). Systematic reviews: synthesis of best evidence for clinical decisions. Annals of internal medicine, 126(5), 376-380.

Da Silva, L. L. S., Lima, A. F. R., Polli, D. A., Razia, P. F. S., Pavão, L. F. A., De Hollanda Cavalcanti, M. A. F., & Toscano, C. M. (2020). Social distancing measures in the fight against covid-19 in brazil: Description and epidemiological analysis by state. Cadernos de Saude Publica, 36(9), 1–15.

de Brito, C. A. A., & Cordeiro, M. T. (2016). One year after the Zika virus outbreak in Brazil: From hypotheses to evidence. Revista Da Sociedade Brasileira de Medicina Tropical, 49(5), 537–543.

Diniz, D. (2016). Vírus Zika e mulheres. Cadernos de Saude Publica, 32(5), 1–4.

Diniz, D. (2017). Zika: From the Brazilian backlands to global threat. Zed Books, 132–135.

Eder, B., Bissinger, A., Riessen, R., & Haap, M. (2018). Malaria tropica und Dengue-Fieber – eine Herausforderung der Intensivmedizin. Intensivmedizin Up2date, 14(03), 263–278.

Friel, S., McMichael, A., Kjellstrom, T., & Prapamontol, T. (2004). Housing and health transition in Thailand. Rev Environ Health, 19, 311–327.

Gorbalenya, A., Baker, S., Baric, R., de Groot, R., Drosten, C., Gulyaeva, A., Haagmans, B., Lauber, C., Leontovich, A., Neuman, B., Penzar, D., Perlman, S., Poon, L., Samborskiy, D., Sidorov, I., Sola, I., & Ziebuhr, J. (2020). Severe acute respiratory syndrome-related coronavirus : The species and its viruses – a statement of the Coronavirus Study Group. Nature Microbiology.

Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., Liu, L., Shan, H., Lei, C., Hui, D. S. C., Du, B., Li, L., Zeng, G., Yuen, K.-Y., Chen, R., Tang, C., Wang, T., Chen, P., Xiang, J., … Zhong, N. (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine, 382(18), 1708–1720.

Gubler, D. J. (2002). The global emergence/resurgence of arboviral diseases as public health problems. Archives of Medical Research, 33(4), 330–342.

Hodgson, E., & Levi, P. E. (1996). Pesticides: An important but underused model for the environmental health sciences. Environmental Health Perspectives, 104(SUPPL. 1), 97–106.

Joob, B., & Wiwanitkit, V. (2020). COVID-19 in medical personnel: observation from Thailand. Journal of Hospital Infection, 104(4), 453.

Joob, Beuy, & Wiwanitkit, V. (2020). COVID-19 can present with a rash and be mistaken for dengue. Journal of the American Academy of Dermatology, 82(5), e177.

Kumar, C. J., Baboo, C. A., Krishnan, B. U., Kumar, A., Joy, S., Jose, T., Philip, A., Sambasivaiah, K., & Hegde, B. M. (2007). The socioeconomic impact of the chikungunya viral epidemic in India. Open Medicine (Ottawa), 1(3), 150–152.

LaBeaud, A. D. (2008). Why arboviruses can be neglected tropical diseases. PLoS Neglected Tropical Diseases, 2(6), 1–2.

Li, R., Pei, S., Chen, B., Song, Y., Zhang, T., Yang, W., & Shaman, J. (2020). Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2). Science, 368(6490), 489–493.

Liang, S., Hapuarachchi, H. C., Rajarethinam, J., Koo, C., Tang, C. S., Chong, C. S., Ng, L. C., & Yap, G. (2018). Construction sites as an important driver of dengue transmission: Implications for disease control. BMC Infectious Diseases, 18(1), 1–10.

Lifson, A. (1996). Mosquitoes, models, and dengue. The Lancet, 142, 1201–1202.

Lim, J. T., Dickens, B. S. L., Chew, L. Z. X., Choo, E. L. W., Koo, J. R., Aik, J., Ng, L. C., & Cook, A. R. (2020). Impact of SARS-CoV-2 interventions on dengue transmission. PLoS Neglected Tropical Diseases, 14(10), 1–17.

Lorenz, C., Azevedo, T. S., & Chiaravalloti-Neto, F. (2020). COVID-19 and dengue fever: A dangerous combination for the health system in Brazil. Travel Medicine and Infectious Disease, 35(January), 19–21.

Louis, V. R., Montenegro Quiñonez, C. A., Kusumawathie, P., Palihawadana, P., Janaki, S., Tozan, Y., Wijemuni, R., Wilder-Smith, A., & Tissera, H. A. (2016). Characteristics of and factors associated with dengue vector breeding sites in the City of Colombo, Sri Lanka. Pathogens and Global Health, 110(2),

Löwy, I. (2019). Zika No Brasil: História Recente De Uma Epidemia (Scielo-E).

Lu, R., Zhao, X., Li, J., Niu, P., Yang, B., Wu, H., Wang, W., Song, H., Huang, B., Zhu, N., Bi, Y., Ma, X., Zhan, F., Wang, L., Hu, T., Zhou, H., Hu, Z., Zhou, W., Zhao, L., … Tan, W. (2020). Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. The Lancet, 395(10224), 565–574.

Magalhaes, T., Chalegre, K. D. M., Braga, C., & Foy, B. D. (2020). The Endless Challenges of Arboviral Diseases in Brazil. Tropical Medicine and Infectious Disease, 5(2), 1–6.

Meyerfeld, B. (2020). Coronavirus : au Brésil, « nous sommes à la limite de la barbarie ». Le Monde. https://www.lemonde.fr/international/article/2020/04/24/coronavirus-au-bresil-nous-sommes-a-la-limite-de-la-barbarie_6037594_3210.html#:~:text=de Covid-19-,Coronavirus %3A au Brésil%2C « nous sommes à la limite de,à un tel défi sanitaire.

Miah, M. A., & Husna, A. (2020). Coinfection, coepidemics of COVID-19, and dengue in dengue-endemic countries: A serious health concern. Journal of Medical Virology.

Ministério da Saúde. (2020a). Monitoramento dos casos de Arboviroses urbanas transmitidas pelo Aedes (dengue, chikungunya e Zika). Boletim Epidemiológico Arboviroses, 51(24), 1–13. https://portalarquivos2.saude.gov.br/images/pdf/2020/janeiro/20/Boletim-epidemiologico-SVS-02-1-.pdf

Ministério da Saúde. (2020b). Painel Coronavírus. https://covid.saude.gov.br/

Ministério do Desenvolvimento Regional. (2019). Diagnóstico dos Serviços de Água e Esgotos - 2018. Sistema Nacional de Informações Sobre Saneamento. http://www.snis.gov.br/diagnostico-anual-agua-e-esgotos/diagnostico-dos-servicos-de-agua-e-esgotos-2018

Murdoch, D. R., & French, N. P. (2020). COVID-19 : another infectious animal-human interface. Nzmj, 133(1510), 12–15.

Myint, K. S. A., Gibbons, R. V., Perng, G. C., & Solomon, T. (2007). Unravelling the neuropathogenesis of Japanese encephalitis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 101(10), 955–956.

Navarro, J. C., Arrivillaga-Henríquez, J., Salazar-Loor, J., & Rodriguez-Morales, A. J. (2020). COVID-19 and dengue, co-epidemics in Ecuador and other countries in Latin America: Pushing strained health care systems over the edge. Travel Medicine and Infectious Disease, 37(March), 101656.

Nicolelis, M. A. L., Raimundo, R. L. G., Peixoto, P. S., & De Andreazzi, C. S. (2020). How Super-Spreader Cities, Highways, Hospital Bed Availability, and Dengue Fever Influenced the Covid-19 Epidemic in Brazil. MedRxiv, 2020.09.19.20197749.

Nogueira, R. M. R., Miagostovich, M. P., Schatzmayr, H. G., Dos Santos, F. B., De Araújo, E. S. M., De Filippis, A. M. B., De Souza, R. V., Zagne, S. M. O., Nicolai, C., Baran, M., & Teixeira Filho, G. (1999). Dengue in the State of Rio de Janeiro, Brazil, 1986-1998. Memorias Do Instituto Oswaldo Cruz, 94(3), 297–304.

Olive, M. M., Baldet, T., Devillers, J., Fite, J., Paty, M. C., Paupy, C., Quénel, P., Quillery, E., Raude, J., Stahl, J. P., Thiann-Bo-morel, M., & Roiz, D. (2020). The COVID-19 pandemic should not jeopardize dengue control. PLoS Neglected Tropical Diseases, 14(9), 1–7.

Ortega, F., & Orsini, M. (2020). Governing COVID-19 without government in Brazil: Ignorance, neoliberal authoritarianism, and the collapse of public health leadership. Global Public Health, 1–21.

Paiva, C. H. A., Teixeira, L. A. da S., & Pires-Alves, F. A. (2020). Especial Covid-19: O Sistema Único de Saúde e o desafio da Covid-19. Fiocruz. http://www.coc.fiocruz.br/index.php/pt/todas-as-noticias/1803-osistema-unico-de-saude-e-o-desafio-da-covid-19.html#.X9IZK1VKjIU

Pan American Health Organization. (2020). Epidemiological Update Dengue. February, 1–21.

Peterson, I., Borrell, L. N., El-Sadr, W., & Teklehaimanot, A. (2009). A temporal-spatial analysis of malaria transmission in Adama, Ethiopia. American Journal of Tropical Medicine and Hygiene, 81(6), 944–949.

Prem, K., Liu, Y., Russell, T. W., Kucharski, A. J., Eggo, R. M., Davies, N., Flasche, S., Clifford, S., Pearson, C. A. B., Munday, J. D., Abbott, S., Gibbs, H., Rosello, A., Quilty, B. J., Jombart, T., Sun, F., Diamond, C., Gimma, A., van Zandvoort, K., … Klepac, P. (2020). The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. The Lancet Public Health, 5(5), e261–e270.

Price-Haywood, E. G., Burton, J., Fort, D., & Seoane, L. (2020). Hospitalization and Mortality among Black Patients and White Patients with Covid-19. New England Journal of Medicine, 382(26), 2534–2543.

Rahi, M., Das, P., & Sharma, A. (2020). COVID-19 mitigation steps provide a blueprint for malaria control and elimination. American Journal of Tropical Medicine and Hygiene, 103(1), 28–30.

Ravi, K. (2020). Ethnic disparities in COVID-19 mortality: are comorbidities to blame? The Lancet, 396(10243), 22.

Ribeiro, H., Lima, V. M., & Waldman, E. A. (2020). In the COVID-19 pandemic in Brazil, do brown lives matter? The Lancet Global Health, 8(8), e976–e977.

Ribeiro, V. S. T., Telles, J. P., & Tuon, F. F. (2020). Arboviral diseases and COVID-19 in Brazil: Concerns regarding climatic, sanitation, and endemic scenario. Journal of Medical Virology, 92(11), 2390–2391.

Ridwan, R. (2020). COVID-19 and dengue: a deadly duo. Tropical Doctor, 50(3), 270–272.

Rocklöv, J., & Sjödin, H. (2020). High population densities catalyse the spread of COVID-19. Journal of Travel Medicine, 27(3), 1–2.

Rodriguez-Morales, A. J., Gallego, V., Escalera-Antezana, J. P., Méndez, C. A., Zambrano, L. I., Franco-Paredes, C., Suárez, J. A., Rodriguez-Enciso, H. D., Balbin-Ramon, G. J., Savio-Larriera, E., Risquez, A., & Cimerman, S. (2020). COVID-19 in Latin America: The implications of the first confirmed case in Brazil. Travel Medicine and Infectious Disease, 35.

Saavedra-Velasco, M., Chiara-Chilet, C., Pichardo-Rodriguez, R., Grandez-Urbina, A., & Inga-Berrospi, F. (2020). [Coinfection between dengue and covid-19: need for approach in endemic zones.]. Revista de La Facultad de Ciencias Medicas (Cordoba, Argentina), 77(1), 52–54.

Sanders, E. J., Rwaguma, E. B., Kawamata, J., Kiwanuka, N., Lutwama, J. J., Ssengooba, F. P., Lamunu, M., Najjemba, R., Were, W. A., Bagambisa, G., & Campbell, G. L. (1999). O’nyong-nyong fever in south-central Uganda, 1996-1997: Description of the epidemic and results of a household-based seroprevalence survey. Journal of Infectious Diseases, 180(5), 1436–1443.

Shadmi, E., Chen, Y., Dourado, I., Faran-Perach, I., Furler, J., Hangoma, P., Hanvoravongchai, P., Obando, C., Petrosyan, V., Rao, K. D., Ruano, A. L., Shi, L., Souza, L. E. de, Spitzer-Shohat, S., Sturgiss, E., Suphanchaimat, R., Uribe, M. V., & Willems, S. (2020). Health equity and COVID-19 : global perspectives. International Journal for Equity in Health, 19(104), 1–16.

Skolarczyk, J., Pekar, J., & Nieradko-Iwanicka, B. (2017). Immune disorders induced by exposure to pyrethroid insecticides. Postepy Higieny i Medycyny Doswiadczalnej (Online), 71, 446–453.

Thomas-Rüddel, D., Winning, J., Dickmann, P., Ouart, D., Kortgen, A., Janssens, U., & Bauer, M. (2020). Coronavirus disease 2019 (COVID-19): update for anesthesiologists and intensivists March 2020. Der Anaesthesist.

Tomori, O. (2002). Yellow fever in Africa: public health impact and prospects for control in the 21st century. Biomédica : Revista Del Instituto Nacional de Salud, 22(2), 178–210.

Van Panhuis, W. G., Choisy, M., Xiong, X., Chok, N. S., Akarasewi, P., Iamsirithaworn, S., Lam, S. K., Chong, C. K., Lam, F. C., Phommasak, B., Vongphrachanh, P., Bouaphanh, K., Rekol, H., Hien, N. T., Thai, P. Q., Duong, T. N., Chuang, J. H., Liu, Y. L., Ng, L. C., & Cummings, D. A. T. (2015). Region-wide synchrony and traveling waves of dengue across eight countries in Southeast Asia. Proceedings of the National Academy of Sciences of the United States of America, 112(42), 13069–13074.

Vogels, C. B. F., Rückert, C., Cavany, S. M., Perkins, T. A., Ebel, G. D., & Grubaugh, N. D. (2019). Arbovirus coinfection and co-transmission: A neglected public health concern? PLoS Biology, 17(1), 1–16.

Wilder-Smith, A., Ooi, E. E., Horstick, O., & Wills, B. (2019). Dengue. The Lancet, 393(10169), 350–363. https://doi.org/10.1016/S0140-6736(18)32560-1

Wilder-Smith, A., Tissera, H., Ooi, E. E., Coloma, J., Scott, T. W., & Gubler, D. J. (2020). Preventing dengue epidemics during the COVID-19 pandemic. American Journal of Tropical Medicine and Hygiene, 103(2), 570–571.

World Health Organization. (2020a). Dengue and severe dengue - Global burden of dengue. https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue

World Health Organization. (2020b). Painel do WHO Coronavirus Disease (COVID-19). https://covid19.who.int/

World Health Organization. (2020c). WHO announces COVID-19 outbreak a pandemic. https://www.euro.who.int/en/health-topics/health-emergencies/coronavirus-covid-19/news/news/2020/3/who-announces-covid-19-outbreak-a-pandemic

Yan, G., Lee, C. K., Lam, L. T. M., Yan, B., Chua, Y. X., Lim, A. Y. N., Phang, K. F., Kew, G. Sen, Teng, H., Ngai, C. H., Lin, L., Foo, R. M., Pada, S., Ng, L. C., & Tambyah, P. A. (2020). Covert COVID-19 and false-positive dengue serology in Singapore. The Lancet Infectious Diseases, 20(5), 536.

Yan, G., Pang, L., Cook, A. R., Ho, H. J., Win, M. S., Khoo, A. L., Wong, J. G. X., Lee, C. K., Yan, B., Jureen, R., Ho, S. S., Lye, D. C., Tambyah, P. A., Leo, Y. S., Fisher, D., Oon, J., Bagdasarian, N., Chow, A., Smitasin, N., & Chai, L. Y. A. (2018). Distinguishing zika and dengue viruses through simple clinical assessment, Singapore. Emerging Infectious Diseases, 24(8), 1565–1568.

Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, G. F., & Tan, W. (2020). A Novel Coronavirus from Patients with Pneumonia in China, 2019. New England Journal of Medicine, 382(8), 727–733.

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30/04/2021

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MILAGRES, T. de F.; SILVA , W. J. da .; LEMOS, A. B. de .; PILZ JÚNIOR, H. L. . .; PROPHIRO , J. S. .; SILVA, O. S. da . A co-epidemia de Dengue e COVID-19 no Brasil: entre os desafios para o seu manejo e as consequências da desigualdade socioeconômica. Research, Society and Development, [S. l.], v. 10, n. 5, p. e19810514728, 2021. DOI: 10.33448/rsd-v10i5.14728. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/14728. Acesso em: 30 jun. 2024.

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