Efeitos de programas baseados em mindfulness oferecidos pela internet para pacientes com câncer: revisão integrativa de ensaios clínicos randomizados.
DOI:
https://doi.org/10.33448/rsd-v11i1.25110Palavras-chave:
Atenção plena; Neoplasias; Intervenção baseada em internet.Resumo
Objetivo: Analisar ensaios clínicos randomizados que avaliaram os efeitos de intervenções baseadas em mindfulness oferecidas pela internet, como tratamento complementar para pacientes com diferentes tipos de câncer. Método: Foram construídas estratégias de buscas específicas para cada base de dados, com descritores controlados e não controlados, operadores booleanos e truncamentos. As buscas para seleção dos estudos foram realizadas nas bases de dados: Pubmed/Medline, PsycoInfo, Web of Science e Clinicaltrials.gov. Resultados: Foram incluídos 8 estudos na revisão integrativa, 2 destes ainda estão em desenvolvimento. Participaram dos estudos finalizados 714 indivíduos com diagnóstico de câncer de quaisquer tipo ou localização. As intervenções online baseadas em mindfulness avaliadas nos estudos incluídos, evidenciaram efeitos positivos em desfechos relevantes para saúde psicológica dos pacientes, tais como ansiedade, depressão, humor, sono, qualidade de vida, estresse, fadiga, crescimento pós-traumático, bem-estar, espiritualidade. Conclusão: Intervenções baseadas em mindfulness por meio da internet tem se mostrado terapias promissoras para a promoção da saúde com foco na qualidade de vida e redução do sofrimento psicológico.
Referências
Boggs, J. M., Ritzwoller, D. P., Beck, A., Dimidjian, S., & Segal, Z. V. (2021). Cost-Effectiveness of a web-based program for residual depressive symptoms: Mindful mood balance. Psychiatric Services (Washington, D.C.), appips202000419. Advance online publication. https://doi.org/10.1176/appi.ps.202000419
Bogosian, A., Hurt, C. S., Hindle, J. V., McCracken, L. M., Vasconcelos e Sa, D. A., Axell, S., Tapper, K., Stevens, J., Hirani, P. S., Salhab, M., Ye, W., & Cubi-Molla, P. (2021). Acceptability and feasibility of a mindfulness intervention delivered via videoconferencing for people with Parkinson’s. Journal of Geriatric Psychiatry and Neurology. 0891988720988901. https://doi.org/10.1177/0891988720988901
Bruggeman-Everts, F. Z., Wolvers, M., van de Schoot, R., Vollenbroek-Hutten, M., & Van der Lee, M. L. (2017). Effectiveness of two web-based interventions for chronic cancer-related fatigue compared to an cctive control condition: Results of the "Fitter na kanker" randomized controlled trial. Journal of Medical Internet Research, 19(10), e336. https://doi.org/10.2196/jmir.7180
Carlson, L. E., Toivonen, K., & Subnis, U. (2019). Integrative approaches to stress management. The Cancer Journal, 25(5), 329-336. doi: 10.1097/PPO.0000000000000395
Carlson, L. E., Subnis, U. B., Piedalue, K. A. L., Vallerand, J., Speca, M., Lupichuk, S., ... & Wolever, R. Q. (2019). The ONE‐MIND Study: Rationale and protocol for assessing the effects of ONlinE MINDfulness‐based cancer recovery for the prevention of fatigue and other common side effects during chemotherapy. European Journal of Cancer Care, 28(4), e13074. https://doi.org/10.1111/ecc.13074
Carver, C. S., & Antoni, M. H. (2004). Finding benefit in breast cancer during the year after diagnosis predicts better adjustment 5 to 8 years after diagnosis. Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association, 23(6), 595–598. https://doi.org/10.1037/0278-6133.23.6.595
Cavanagh, K., Churchard, A., O'Hanlon, P., Mundy, T., Votolato, P., Jones, F., Gu, J., & Strauss, C. (2018). A randomised controlled trial of a brief online mindfulness-based intervention in a non-clinical population: Replication and extension. Mindfulness, 9(4), 1191–1205. https://doi.org/10.1007/s12671-017-0856-1
Cillessen, L., Schellekens, M., Van de Ven, M., Donders, A., Compen, F. R., Bisseling, E. M., Van der Lee, M. L., & Speckens, A. (2018). Consolidation and prediction of long-term treatment effect of group and online mindfulness-based cognitive therapy for distressed cancer patients. Acta Oncologica (Stockholm, Sweden), 57(10), 1293–1302. https://doi.org/10.1080/0284186X.2018.1479071
Cillessen, L., Johannsen, M., Speckens, A., & Zachariae, R. (2019). Mindfulness-based interventions for psychological and physical health outcomes in cancer patients and survivors: A systematic review and meta-analysis of randomized controlled trials. Psycho-Oncology, 28(12), 2257–2269. https://doi.org/10.1002/pon.5214
Cillessen, L., van de Ven, M. O., Compen, F. R., Bisseling, E. M., van der Lee, M. L., & Speckens, A. E. (2020). Predictors and effects of usage of an online mindfulness intervention for distressed cancer patients: Usability study. Journal of Medical Internet Research, 22(10), e17526. https://doi.org/10.2196/17526
Compen, F. R., Bisseling, E. M., Van der Lee, M. L., Adang, E. M., Donders, A. R., & Speckens, A. E. (2015). Study protocol of a multicenter randomized controlled trial comparing the effectiveness of group and individual internet-based Mindfulness-Based Cognitive Therapy with treatment as usual in reducing psychological distress in cancer patients: the BeMind study. BMC Psychology, 3(1), 27. https://doi.org/10.1186/s40359-015-0084-1
Compen, F.R., Bisseling, E., Schellekens, M., Donders, R., Carlson, L., Lee, M., Speckens, A. (2018) Face-to-face and internet-based Mindfulness-Based Cognitive Therapy compared with treatment as usual in reducing psychological distress in patients with cancer: A multicenter randomized controlled trial. Journal of Clinical Oncology, 36(23):2413-2421. DOI:10.1200/JCO.2017.76.5669
Dunne, J., Chih, H. J., Begley, A., Daly, A., Gerlach, R., Schütze, R., Castell, E., Byrne, J., & Black, L. J. (2021). A randomised controlled trial to test the feasibility of online mindfulness programs for people with multiple sclerosis. Multiple sclerosis and related disorders, 48,102728. https://doi.org/10.1016/j.msard.2020.102728
Gardner-Nix, J., Backman, S., Barbati, J., & Grummitt, J. (2008). Evaluating distance education of a mindfulness-based meditation programme for chronic pain management. Journal of Telemedicine and Telecare, 14(2), 88–92. https://doi.org/10.1258/jtt.2007.070811.
Garland, S. N., Carlson, L. E., Cook, S., Lansdell, L., & Speca, M. (2007). A non-randomized comparison of mindfulness-based stress reduction and healing arts programs for facilitating post-traumatic growth and spirituality in cancer outpatients. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer, 15(8), 949–961. https://doi.org/10.1007/s00520-007-0280-5
Higgins, J. P., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M. J., & Welch, V. A. (Eds.). (2019). Cochrane handbook for systematic reviews of interventions. John Wiley & Sons.
Jiang, A., Rosario, M., Stahl, S., Gill, J. M., & Rusch, H. L. (2021). The effect of virtual mindfulness-based interventions on sleep quality: A systematic review of randomized controlled trials. Current Psychiatry Reports, 23(9), 62. https://doi.org/10.1007/s11920-021-01272-6
Johns, S. A., Tarver, W. L., Secinti, E., Mosher, C. E., Stutz, P. V., Carnahan, J. L., Talib, T. L., Shanahan, M. L., Faidley, M. T., Kidwell, K. M., & Rand, K. L. (2021). Effects of mindfulness-based interventions on fatigue in cancer survivors: A systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Oncology/Hematology, 160,103290. https://doi.org/10.1016/j.critrevonc.2021.103290
Kinner, E. M., Armer, J. S., McGregor, B. A., Duffecy, J., Leighton, S., Corden, M. E., Gauthier Mullady J., Penedo F.J., & Lutgendorf, S. K. (2018). Internet-based group intervention for ovarian cancer survivors: Feasibility and preliminary results. JMIR Cancer, 4(1), e8430. DOI:10.2196/cancer.8430
Kubo, A., Kurtovich, E., McGinnis, M., Aghaee, S., Altschuler, A., Quesenberry Jr, C., Kolevska, T., Liu, R., Greyz-Yusupov, N., & Avins, A. (2020). Pilot pragmatic randomized trial of mHealth mindfulness‐based intervention for advanced cancer patients and their informal caregivers. Psycho‐Oncology. https://doi.org/10.1002/pon.5557
Kuderer, N. M., Choueiri, T. K., Shah, D. P., Shyr, Y., Rubinstein, S. M., Rivera, D. R., Sethe, S., Hsu, C.Y, Desai, A., Lopes Jr., G.L., Grivas, P., Painter C.A., Peters, S., Thompson M.A., Bakouny, Z., Batist, G., Bekaii-Saab, T., Bilen, M.A., Bouganim, N., ... & Loaiza-Bonilla, A. (2020). Clinical impact of COVID-19 on patients with cancer (CCC19): A cohort study. The Lancet, 395(10241), 1907-1918. https://doi.org/10.1016/S0140-6736(20)31187-9
Labelle, L. E., Lawlor-Savage, L., Campbell, T. S., Faris, P., & Carlson, L. E. (2015). Does self-report mindfulness mediate the effect of Mindfulness-Based Stress Reduction (MBSR) on spirituality and posttraumatic growth in cancer patients? The Journal of Positive Psychology, 10(2), 153-166. DOI:10.1080/17439760.2014.927902
Lengacher, C. A., Johnson-Mallard, V., Post-White, J., Moscoso, M. S., Jacobsen, P. B., Klein, T. W., Widen, R. H., Fitzgerald, S. G., Shelton, M. M., Barta, M., Goodman, M., Cox, C. E., & Kip, K. E. (2009). Randomized controlled trial of Mindfulness-Based Stress Reduction (MBSR) for survivors of breast cancer. Psycho-Oncology, 18(12), 1261–1272. https://doi.org/10.1002/pon.1529
Lengacher, C. A., Reich, R. R., Paterson, C. L., Ramesar, S., Park, J. Y., Alinat, C., Johnson-Mallard, V., Moscoso, M., Budhrani-Shani, P., Miladinovic, B., Jacobsen, P. B., Cox, C. E., Goodman, M., & Kip, K. E. (2016). Examination of broad symptom improvement resulting from Mindfulness-Based Stress Reduction in breast cancer survivors: A randomized controlled trial. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 34(24), 2827–2834. https://doi.org/10.1200/JCO.2015.65.7874
Lengacher, C. A., Reich, R. R., Paterson, C. L., Shelton, M., Shivers, S., Ramesar, S., Pleasant, M. L., Budhrani-Shani, P., Groer, M., Post-White, J., Johnson-Mallard, V., Kane, B., Cousin, L., Moscoso, M. S., Romershausen, T. A., & Park, J. Y. (2019). A large randomized trial: Effects of Mindfulness-Based Stress Reduction (MBSR) for breast cancer (BC) survivors on salivary cortisol and IL-6. Biological Research for Nursing, 21(1), 39–49. https://doi.org/10.1177/1099800418789777
Leykin, Y., Thekdi, S. M., Shumay, D. M., Muñoz, R. F., Riba, M., & Dunn, L. B. (2012). Internet interventions for improving psychological well‐being in psycho‐oncology: Review and recommendations. Psycho‐Oncology, 21(9), 1016-1025. https://doi.org/10.1002/pon.1993
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P., Clarke M., Devereaux P.J., Kleijnen J., & Moher, D. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. Journal of Clinical Epidemiology, 62(10), e1-e34. https://doi.org/10.1016/j.jclinepi.2009.06.006
Ma, Y., She, Z., Siu, A. F., Zeng, X., & Liu, X. (2018). Effectiveness of online mindfulness-based interventions on psychological distress and the mediating role of emotion regulation. Frontiers in Psychology, 9,2090. https://doi.org/10.3389/fpsyg.2018.02090
Mehta, V., Goel, S., Kabarriti, R., Cole, D., Goldfinger, M., Acuna-Villaorduna, A., Pradhan K., Thota, R., Reissman, S., Sparano, J.A., Gartrell, B.A., Smith, R.V, Ohri, N., Garg, M., Racine, A.D., Kalnicki, S., Perez-Soler R., Halmos, B., & Verma, A. (2020). Case fatality rate of cancer patients with COVID-19 in a New York hospital system. Cancer Discovery, 10(7), 935-941. DOI: 10.1158/2159-8290.CD-20-0516
Messer, D., Horan, J. J., Larkey, L. K., & Shanholtz, C. E. (2019). Effects of internet training in mindfulness meditation on variables related to cancer recovery. Mindfulness, 10(10), 2143-2151. https://doi.org/10.1007/s12671-019-01182-y
Metin, Z. G., Karadas, C., Izgu, N., Ozdemir, L., & Demirci, U. (2019). Effects of progressive muscle relaxation and mindfulness meditation on fatigue, coping styles, and quality of life in early breast cancer patients: An assessor blinded, three-arm, randomized controlled trial. European Journal of Oncology Nursing, 42,116-125. https://doi.org/10.1016/j.ejon.2019.09.003
Mikolasek, M., Berg, J., Witt, C. M., & Barth, J. (2018). Effectiveness of mindfulness- and relaxation-based ehealth interventions for patients with medical conditions: A systematic review and synthesis. International Journal of Behavioral Medicine, 25(1), 1–16. https://doi.org/10.1007/s12529-017-9679-7
Morrill, E. F., Brewer, N. T., O'Neill, S. C., Lillie, S. E., Dees, E. C., Carey, L. A., & Rimer, B. K. (2008). The interaction of post‐traumatic growth and post‐traumatic stress symptoms in predicting depressive symptoms and quality of life. Psycho‐Oncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer, 17(9), 948-953. https://doi.org/10.1002/pon.1313
Ngamkham, S., Holden, J. E., & Smith, E. L. (2019). A systematic review: Mindfulness intervention for cancer-related pain. Asia-Pacific Journal of Oncology Nursing, 6(2), 161–169. https://doi.org/10.4103/apjon.apjon_67_18
Nissen, E. R., O'Connor, M., Kaldo, V., Højris, I., Borre, M., Zachariae, R., & Mehlsen, M. (2020). Internet-delivered mindfulness-based cognitive therapy for anxiety and depression in cancer survivors: A randomized controlled trial. Psycho-Oncology, 29(1), 68–75. https://doi.org/10.1002/pon.5237
Parodi, S. M., & Liu, V. X. (2020). From containment to mitigation of COVID-19 in the US. Jama, 323(15), 1441-1442. doi:10.1001/jama.2020.3882
Russell, L., Ugalde, A., Milne, D., Krishnasamy, M., Austin, D. W., Chambers, R., Orellana, L. & Livingston, P. M. (2018). Feasibility of an online mindfulness-based program for patients with melanoma: Study protocol for a randomised controlled trial. Trials, 19(1), 1-11. https://doi.org/10.1186/s13063-018-2575-x
Schell, L. K., Monsef, I., Wöckel, A., & Skoetz, N. (2019). Mindfulness-based stress reduction for women diagnosed with breast cancer. The Cochrane Database of Systematic Reviews, 3(3), CD011518. https://doi.org/10.1002/14651858.CD011518.pub2
Simard, S., Thewes, B., Humphris, G., Dixon, M., Hayden, C., Mireskandari, S., & Ozakinci, G. (2013). Fear of cancer recurrence in adult cancer survivors: A systematic review of quantitative studies. Journal of Cancer Survivorship: Research and Practice, 7(3), 300–322. https://doi.org/10.1007/s11764-013-0272-z
Spijkerman, M. P., Pots, W. T., & Bohlmeijer, E. T. (2016). Effectiveness of online mindfulness-based interventions in improving mental health: A review and meta-analysis of randomised controlled trials. Clinical Psychology Review, 45,102–114. https://doi.org/10.1016/j.cpr.2016.03.009
Subnis U.B., Farb N.A., Piedalue K.L., Speca M., Lupichuk S., Tang P.A., Faris P., Thoburn M., Saab B.J. & Carlson L.E. (2020). A smartphone app–based mindfulness intervention for cancer survivors: protocol for a randomized controlled trial. JMIR Research Protocols, 9(5), e15178. doi: 10.2196/15178
Tauber, N. M., O'Toole, M. S., Dinkel, A., Galica, J., Humphris, G., Lebel, S., Maheu, C., Ozakinci, G., Prins, J., Sharpe, L., Smith, A. B., Thewes, B., Simard, S., & Zachariae, R. (2019). Effect of psychological intervention on fear of cancer recurrence: A systematic review and meta-analysis. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 37(31), 2899–2915. https://doi.org/10.1200/JCO.19.00572
Trevino, K. M., Raghunathan, N., Latte-Naor, S., Polubriaginof, F. C., Jensen, C., Atkinson, T. M., Emard, N., Seluzicki, C.M., Ostroff J.S. & Mao, J. J. (2021). Rapid deployment of virtual mind-body interventions during the COVID-19 outbreak: feasibility, acceptability, and implications for future care. Supportive Care in Cancer, 29(2), 543-546. https://doi.org/10.1007/s00520-020-05740-2
Ueda, M., Martins, R., Hendrie, P. C., McDonnell, T., Crews, J. R., Wong, T. L., McCreery, B., Jagels, B., Crane, A., Byrd, D. R., Pergam, S. A., Davidson, N. E., Liu, C., & Stewart, F. M. (2020). Managing cancer care during the COVID-19 pandemic: Agility and collaboration toward a common goal. Journal of the National Comprehensive Cancer Network: JNCCN, 1–4. Advance online publication. https://doi.org/10.6004/jnccn.2020.7560
Xie, C., Dong, B., Wang, L., Jing, X., Wu, Y., Lin, L., & Tian, L. (2020). Mindfulness-Based Stress Reduction can alleviate cancer- related fatigue: A meta-analysis. Journal of Psychosomatic Research, 130, 109916. https://doi.org/10.1016/j.jpsychores.2019.109916
Xunlin, N. G., Lau, Y., & Klainin-Yobas, P. (2020). The effectiveness of mindfulness-based interventions among cancer patients and survivors: A systematic review and meta-analysis. Supportive Care in Cancer, 28(4), 1563-1578. https://doi.org/10.1007/s00520-019-05219-9
Zernicke, K. A., Campbell, T. S., Speca, M., McCabe-Ruff, K., Flowers, S., Dirkse, D. A., & Carlson, L. E. (2013). The eCALM Trial-eTherapy for cancer appLying mindfulness: online mindfulness-based cancer recovery program for underserved individuals living with cancer in Alberta: Protocol development for a randomized wait-list controlled clinical trial. BMC Complementary and Alternative Medicine, 13, 34. https://doi.org/10.1186/1472-6882-13-34
Zernicke, K. A., Campbell, T. S., Speca, M., McCabe-Ruff, K., Flowers, S., & Carlson, L. E. (2014). A randomized wait-list controlled trial of feasibility and efficacy of an online mindfulness-based cancer recovery program: The eTherapy for cancer applying mindfulness trial. Psychosomatic Medicine, 76(4), 257–267. https://doi.org/10.1097/PSY.0000000000000053
Zernicke, K.A., Campbell, T.S., Speca, M., Kelley, M., Ruff, M., Flowers, E., Tamagawa, R. & Carlson, L.E., et al. (2016) The eCALM Trial: eTherapy for Cancer Applying Mindfulness. Exploratory analyses of the associations between online Mindfulness-Based Cancer Recovery participation and changes in mood, stress symptoms, mindfulness, posttraumatic growth, and spirituality. Mindfulness, 7, 1071–1081. https://doi.org/10.1007/s12671-016-0545-5
Wolvers, M., Bruggeman-Everts, F. Z., Van der Lee, M. L., Van de Schoot, R., & Vollenbroek-Hutten, M. M. (2015). Effectiveness, mediators, and effect predictors of internet interventions for chronic cancer-related fatigue: The design and an analysis plan of a 3-armed randomized controlled trial. JMIR Research Protocols, 4(2), e77. https://doi.org/10.2196/resprot.4363
World Health Organization. (2020). Considerations for quarantine of individuals in the context of containment for coronavirus disease ( COVID-19): Interim guidance, 19 March 2020 (No. WHO/2019-nCoV/IHR_Quarantine/2020.2). World Health Organization.
Young, A. M., Ashbury, F. D., Schapira, L., Scotté, F., Ripamonti, C. I., & Olver, I. N. (2020). Uncertainty upon uncertainty: Supportive care for cancer and COVID-19. Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer, 28(9), 4001–4004. https://doi.org/10.1007/s00520-020-05604-9
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