Avanços e recentes desafios sobre nanoestruturas à base de quitosana preparadas por complexação polieletrolítica e gelatinização iônica para estabilização de antocianinas
DOI:
https://doi.org/10.33448/rsd-v11i10.33092Palavras-chave:
Encapsulamento; Nanopartículas biopoliméricas; Nanocomplexos; Biopolímeros.Resumo
Antocianinas são polifenóis solúveis em água, responsáveis pela coloração de diversas frutas, flores e vegetais. Além de corantes naturais, antocianinas também estão relacionadas a prevenção de diversas doenças crônicas. Contudo, antocianinas são extremamente sensíveis a variações de ph, temperatura, luz, enzimas e outras variáveis do meio em que se encontram, sendo necessário empregar artifícios e tecnologias para expandir sua aplicação tanto no setor de alimentos como farmacêutico. Nesse contexto, nanopartículas biopoliméricas podem ser usadas para proteger antocianinas e até mesmo intensificar as funções conferidas a elas. Dentre as técnicas usadas, complexação polieletrolítica (PC) e gelatinização iônica (IG) tomam posição de destaque devido a praticidade, rapidez, baixo custo e possibilidade de uso de polímeros versáteis, biocompatíveis e naturais, como a quitosana. Desse modo, pontuar e entender os principais fatores que afetam a estabilidade das nanopartículas à base de quitosana produzidas por PC e IG, e conhecer as estratégias que podem ser adotadas para contornar esses problemas são de extrema importância. Diante do exposto, essa revisão tem como objetivo fornecer uma visão geral sobre antocianinas e nanopartículas biopoliméricas com ênfase nas técnicas de PC e IG, identificando os principais desafios que precisam ser enfrentados ao incorporar antocianinas nessas nanopartículas produzidas em base de quitosana, e direcionar o desenvolvimento de novos projetos com foco na estabilização de antocianinas.
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