Exposição a agrotóxicos e excesso de peso - Uma revisão sistemática

Autores

DOI:

https://doi.org/10.33448/rsd-v11i14.36493

Palavras-chave:

Agroquímicos; Disruptores endócrinos; Sobrepeso; Comorbidades associadas.

Resumo

Este estudo resulta de uma revisão sistemática com objetivo de investigar a possível relação entre a exposição a agrotóxicos e a indução de excesso de peso corporal em indivíduos adultos. Utilizou-se a estratégia PICO (Population, Interventions/exposição, Comparisons, Outcomes) e as bases de dados PUBMED, SCIENCE DIRECT e SCOPUS para realizar a busca. Nesta revisão, foram incluídos 15 estudos. Os dados apresentados demonstraram que 86,66% (13/15) dos estudos correlacionaram positivamente o excesso de peso e a exposição a agrotóxicos. Além disso, observamos relação entre a exposição aos agrotóxicos e o mecanismo de desregulação da glicose (aumento dos níveis de glicose, insulina e índice de resistência à insulina de avaliação do modelo de homeostase (HOMA-IR)) e desregulação da homeostase lipídica (aumento dos níveis de triglicerídeos e diminuição dos níveis de lipoproteína de alta densidade (HDL)). Esses achados propuseram um aumento no risco de doenças cardíacas e diabetes. Além disso, esses resultados mostram que a exposição a agrotóxicos também pode aumentar o risco de desenvolvimento de excesso de peso. No entanto, mais estudos são necessários para determinar o possível mecanismo.

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07/11/2022

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SKONIESKI, C. .; SILVA, L.; FAGUNDES, K. R.; NUNES, A. T. .; FINHLER, S. .; ROVERSI , . K. .; GALLINA, A. L. .; HIRATA, M. H. .; FERREIRA, G. M.; BENVEGNÚ, D. M. . Exposição a agrotóxicos e excesso de peso - Uma revisão sistemática . Research, Society and Development, [S. l.], v. 11, n. 14, p. e596111436493, 2022. DOI: 10.33448/rsd-v11i14.36493. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/36493. Acesso em: 25 nov. 2024.

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