Clinical profile of patients with obesity and COVID-19 in an outpatient setting in northeastern Brazil: a retrospective cohort study

Mellyne Henriques  Guerra; Marília Souza Alves Gois; Brunna Karolyne Souza  Hora; Catharine Mattos  Melo; Ana Monize Ribeiro  Fonseca; Rafaela Mota de  Jesus; Rívia Siqueira  Amorim; Ingrid Cristiane Pereira  Gomes; Karla Freire Rezende; Nathalie Oliveira de  Santana

doi:10.33448/rsd-v11i15.36811

Autores

Mellyne Henriques Guerra Tiradentes University https://orcid.org/0000-0002-0578-281X
Marília Souza Alves Gois Tiradentes University https://orcid.org/0000-0001-9242-3729
Brunna Karolyne Souza Hora Tiradentes University https://orcid.org/0000-0002-9183-4822
Catharine Mattos Melo Tiradentes University https://orcid.org/0000-0002-3205-4260
Ana Monize Ribeiro Fonseca Tiradentes University https://orcid.org/0000-0002-7565-8435
Rafaela Mota de Jesus Federal University of Sergipe https://orcid.org/0000-0002-3935-2447
Rívia Siqueira Amorim Federal University of Sergipe https://orcid.org/0000-0003-3109-9886
Ingrid Cristiane Pereira Gomes Federal University of Sergipe https://orcid.org/0000-0001-9328-8581
Karla Freire Rezende Federal University of Sergipe https://orcid.org/0000-0002-2876-5780
Nathalie Oliveira de Santana Federal University of Sergipe https://orcid.org/0000-0003-1447-1754

DOI:

https://doi.org/10.33448/rsd-v11i15.36811

Palavras-chave:

Assistência ambulatorial; COVID-19; Obesidade; Pandemia; Fator de risco.

Resumo

Objetivo: Analisar o perfil clínico dos pacientes obesos com COVID-19 em assistência ambulatorial durante a primeira onda da pandemia. Métodos: Estudo observacional retrospectivo, realizado em ambiente ambulatorial de Aracaju/SE, Brasil. Os pacientes com COVID-19 receberam atendimento médico em centro de referência de abril a agosto de 2020 e foram seguidos remotamente. Os dados clínicos deles foram analisados pelo programa Jamovi 1.2.27. Resultados: De 1.134 pacientes com COVID-19, 288 (25,4%) eram obesos, 59,7% eram mulheres. Hipertensão, diabetes, dislipidemia, e doença renal crônica foram mais frequentes no grupo de obesos. Dispneia e diarreia foram mais frequentes em indivíduos obesos, enquanto odinofagia, náusea e vômito foram mais comuns em não obesos. Médicos assistentes receitaram mais antibióticos, ivermectina, corticosteroides e heparina para pacientes obesos. A admissão hospitalar (6,6% vs. 3,1%; p=0,008) e o uso de oxigenoterapia (5,1% vs. 2,1%; p=0,011) foram mais frequentes no grupo da obesidade. A obesidade foi associada independentemente à admissão hospitalar em análise multivariada (OR: 2.561, IC 95% 1.352 - 4.853; p=0.004). A taxa de letalidade foi maior em indivíduos obesos (2,1% vs. 0,7%; p=0,049). Conclusão: Nesta coorte ambulatorial de pacientes com COVID-19, houve mais comorbidades entre indivíduos com obesidade. Apesar da baixa freqüência de resultados desfavoráveis em geral, a obesidade aumentou o risco de internação hospitalar e houve mais mortes entre os pacientes com obesidade.

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Perfil clínico de pacientes com obesidade e COVID-19 em ambiente ambulatorial no nordeste do Brasil: um estudo de coorte retrospectivo

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