Aplicações clínicas da curcumina (Curcuma longa) em desordens orais
DOI:
https://doi.org/10.33448/rsd-v9i7.3789Palavras-chave:
Curcumina; Fitoterapia; Doenças da boca.Resumo
A curcumina é um pigmento amarelo que está presente no rizoma do açafrão-da-terra (Curcuma longa), uma planta relacionada à família do gengibre (Zingiberaceae), originária da Índia. É usada, principalmente, na culinária e na estética, mas também é bastante difundida na medicina popular, na forma de chás, géis e pomadas. O objetivo desse trabalho foi averiguar na literatura qual o potencial clínico da curcumina em desordens no complexo buco-maxilofacial. Para isso, realizou-se uma pesquisa integrativa da literatura publicada no intervalo de 2000 a 2020 nos bancos de dados online PubMed (National Library of Medicine) e ScienceDirect. Usando descritores e sinônimos MeSH, seguindo 3 campos semânticos: “Curcumin” em associação com “Oral and Maxillofacial Pathology” e “Pharmacological Therapy”. Dos 986 artigos encontrados, 20 foram incluídos neste artigo após a aplicação dos critérios de inclusão. Na pesquisa realizada, foram observados resultados significativamente positivos em tratamentos de patologias como leucoplasia, carcinoma adenoide cístico, líquen plano, fibrose submucosa, mucosite oral e candidíase. Além disso, complicações pós-cirúrgicas como dor, edema inflamatório e osteíte alveolar também tiveram sinais e sintomas atenuados devido ao uso de curcuminóides. Nesse sentido, a curcumina se aplica à odontologia como anti-inflamatório, antifúngico, antineoplásico e cicatrizante.
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