A relação entre COVID-19 e alterações no ciclo menstrual em um contexto de pandemia: Uma revisão sistemática da literatura
DOI:
https://doi.org/10.33448/rsd-v11i17.39145Palavras-chave:
Ciclo menstrual; Covid-19; SARS-CoV-2; Revisão sistemática.Resumo
Desde que foi decretada em dezembro de 2019, a pandemia da COVID-19 tomou enormes proporções. Neste contexto em que todos os aspectos da vida humana foram afetados, torna-se importante, no âmbito da saúde feminina, compreender quais os impactos da COVID-19 no ciclo menstrual, visto sua importância na vida das mulheres. O objetivo deste trabalho foi buscar estudos capazes de descrever as mudanças no ciclo menstrual observadas devido à COVID-19 e a fisiopatologia que está ligada a essas alterações, bem como suas consequências. Um ciclo menstrual normal é um indicador de boa saúde, ao passo que distúrbios no ciclo menstrual podem indicar condições subjacentes.. Diferentes tipos de células encontradas nas gônadas mostram a expressão da enzima conversora de angiotensina 2 (ECA2) e serina protease transmembrana subtipo 2 (TMPRSS2), que fornecem vias de entrada fundamentais para o vírus SARS-CoV-2 na célula. Além disso, os efeitos biológicos sistêmicos da infecção por COVID-19 podem influenciar no eixo hipotálamo-hipófise-adrenal, aumentando o estresse e, consequentemente, o cortisol, exercendo um efeito global sobre o funcionamento do corpo. A revisão sistemática demonstrou que a COVID-19 influencia, de maneira reversível, no aumento ou diminuição na duração do ciclo, irregularidade menstrual, aumento do fluxo menstrual, escapes intermenstruais e sintomas mais intensos no período pré-menstrual, como dor abdominal e aumento da tensão pré-menstrual. Além disso, o impacto da pandemia na saúde mental e no comportamento sexual podem afetar a reprodução humana, sendo assim, a pandemia foi associada a um declínio na satisfação sexual, menor libido e menor frequência sexual.
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