Rastreio de pré-eclâmpsia no primeiro trimestre
DOI:
https://doi.org/10.33448/rsd-v12i1.39242Palavras-chave:
Pré-eclâmpsia; Primeiro trimestre da gravidez; Gravidez de alto risco.Resumo
O presente estudo teve como objetivo discorrer sobre o rastreio de pré-eclâmpsia no primeiro trimestre de gestação. A pré-eclâmpsia é considerada uma das principais causas de morbimortalidade materna e fetal. Devido a isto, faz-se importante identificar gestantes em risco de desenvolver pré-eclâmpsia durante o primeiro trimestre da gravidez, permitindo assim uma intervenção terapêutica oportuna. Organizações profissionais, como o American College of Obstetricians and Gynecologists e o National Institute for Health and Care Excellence, propuseram a triagem para pré-eclâmpsia com base em fatores de risco materno. No entanto, poucos exames laboratoriais possuem alta especificidade e sensibilidade para identificar tal patologia precocemente. Vale ressaltar que o modelo de previsão do primeiro trimestre da Fetal Medicine Foundation, que consiste em uma combinação de fatores maternos e medições da pressão arterial média, índice de pulsatilidade da artéria uterina e fator de crescimento placentário sérico, passou por validação interna e externa bem-sucedida, tal teste de triagem apresenta-se superior ao método tradicional (apenas por fatores de risco maternos). Quando identificadas, as gestantes com alto risco para desenvolver pré-eclâmpsia devem fazer o uso de aspirina de baixa dose iniciada antes das 16 semanas de gestação, assim como o uso de cálcio em gestantes com baixa ingesta visando a redução na taxa de pré-eclâmpsia pré-termo. Com isso, objetivando um desempenho ideal na triagem devem ser estabelecidos protocolos padronizados para medições de biomarcadores e avaliação regular da qualidade dos biomarcadores.
Referências
Abalos, E., Cuesta, C., Grosso, A. L., Chou, D., & Say, L. (2013). Global and regional estimates of preeclampsia and eclampsia: a systematic review. European journal of obstetrics, gynecology, and reproductive biology, 170(1), 1–7. https://doi.org/10.1016/j.ejogrb.2013.05.005
Ackerman, C. M., Platner, M. H., Spatz, E. S., Illuzzi, J. L., Xu, X., Campbell, K. H., Smith, G. N., Paidas, M. J., & Lipkind, H. S. (2019). Severe cardiovascular morbidity in women with hypertensive diseases during delivery hospitalization. American journal of obstetrics and gynecology, 220(6), 582.e1–582.e11. https://doi.org/10.1016/j.ajog.2019.02.010
Allen, R. E., Zamora, J., Arroyo-Manzano, D., Velauthar, L., Allotey, J., Thangaratinam, S., & Aquilina, J. (2017). External validation of preexisting first trimester preeclampsia prediction models. European journal of obstetrics, gynecology, and reproductive biology, 217, 119–125. https://doi.org/10.1016/j.ejogrb.2017.08.031
Allotey, J., Snell, K. I., Smuk, M., Hooper, R., Chan, C. L., Ahmed, A., Chappell, L. C., von Dadelszen, P., Dodds, J., Green, M., Kenny, L., Khalil, A., Khan, K. S., Mol, B. W., Myers, J., Poston, L., Thilaganathan, B., Staff, A. C., Smith, G. C., Ganzevoort, W., … Thangaratinam, S. (2020). Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. Health technology assessment (Winchester, England), 24(72), 1–252. https://doi.org/10.3310/hta24720
Baker, P. N., & Johnson, I. R. (1994). The use of the hand-grip test for predicting pregnancy-induced hypertension. European journal of obstetrics, gynecology, and reproductive biology, 56(3), 169–172. https://doi.org/10.1016/0028-2243(94)90165-1
Bartsch, E., Medcalf, K. E., Park, A. L., Ray, J. G., & High Risk of Pre-eclampsia Identification Group (2016). Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies. BMJ (Clinical research ed.), 353, i1753. https://doi.org/10.1136/bmj.i1753
Berks, D., Steegers, E. A. P., Molas, M., & Visser, W. (2009). Resolution of hypertension and proteinuria after preeclampsia. Obstetrics and gynecology, 114(6), 1307–1314. https://doi.org/10.1097/AOG.0b013e3181c14e3e
Braun, T., Brauer, M., Fuchs, I., Czernik, C., Dudenhausen, J. W., Henrich, W., & Sarioglu, N. (2010). Mirror syndrome: a systematic review of fetal associated conditions, maternal presentation and perinatal outcome. Fetal diagnosis and therapy, 27(4), 191–203. https://doi.org/10.1159/000305096
Briceño-Pérez, C., Briceño-Sanabria, L., & Vigil-De Gracia, P. (2009). Prediction and prevention of preeclampsia. Hypertension in pregnancy, 28(2), 138–155. https://doi.org/10.1080/10641950802022384
Brunelli, V. B., & Prefumo, F. (2015). Quality of first trimester risk prediction models for pre-eclampsia: a systematic review. BJOG : an international journal of obstetrics and gynaecology, 122(7), 904–914. https://doi.org/10.1111/1471-0528.13334
Conde-Agudelo, A., Villar, J., & Lindheimer, M. (2004). World Health Organization systematic review of screening tests for preeclampsia. Obstetrics and gynecology, 104(6), 1367–1391. https://doi.org/10.1097/01.AOG.0000147599.47713.5d
Cunningham, F. G., & Lindheimer, M. D. (1992). Hypertension in pregnancy. The New England journal of medicine, 326(14), 927–932. https://doi.org/10.1056/NEJM199204023261405
Cunningham G.C., Roberts J.M. & Lindheimer M.D. (2009). The clinical spectrum of preeclampsia. Elsevier. San Diego, CA.
Duckitt, K., & Harrington, D. (2005). Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ (Clinical research ed.), 330(7491), 565. https://doi.org/10.1136/bmj.38380.674340.E0
Duley L. (2009). The global impact of pre-eclampsia and eclampsia. Seminars in perinatology, 33(3), 130–137. https://doi.org/10.1053/j.semperi.2009.02.010
Chaemsaithong, P., Pooh, R. K., Zheng, M., Ma, R., Chaiyasit, N., Tokunaka, M., Shaw, S. W., Seshadri, S., Choolani, M., Wataganara, T., Yeo, G. S. H., Wright, A., Leung, W. C., Sekizawa, A., Hu, Y., Naruse, K., Saito, S., Sahota, D., Leung, T. Y., & Poon, L. C. (2019). Prospective evaluation of screening performance of first-trimester prediction models for preterm preeclampsia in an Asian population. American journal of obstetrics and gynecology, 221(6), 650.e1–650.e16. https://doi.org/10.1016/j.ajog.2019.09.041
Chaemsaithong, P., Sahota, D. S., & Poon, L. C. (2022). First trimester preeclampsia screening and prediction. American journal of obstetrics and gynecology, 226(2S), S1071–S1097.e2. https://doi.org/10.1016/j.ajog.2020.07.020
Chaiworapongsa, T., Romero, R., Kim, Y. M., Kim, G. J., Kim, M. R., Espinoza, J., Bujold, E., Gonçalves, L., Gomez, R., Edwin, S., & Mazor, M. (2005). Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 17(1), 3–18. https://doi.org/10.1080/14767050400028816
Chaiworapongsa, T., Romero, R., Tarca, A. L., Kusanovic, J. P., Gotsch, F., Mittal, P., Kim, S. K., Vaisbuch, E., Mazaki-Tovi, S., Erez, O., Dong, Z., Kim, C. J., Yeo, L., & Hassan, S. S. (2010). A decrease in maternal plasma concentrations of sVEGFR-2 precedes the clinical diagnosis of preeclampsia. American journal of obstetrics and gynecology, 202(6), 550.e1–550.e5510. https://doi.org/10.1016/j.ajog.2010.04.002
Chaiworapongsa, T., Chaemsaithong, P., Yeo, L., & Romero, R. (2014). Pre-eclampsia part 1: current understanding of its pathophysiology. Nature reviews. Nephrology, 10(8), 466–480. https://doi.org/10.1038/nrneph.2014.102
Farina, A., Rapacchia, G., Freni Sterrantino, A., Pula, G., Morano, D., & Rizzo, N. (2011). Prospective evaluation of ultrasound and biochemical-based multivariable models for the prediction of late pre-eclampsia. Prenatal diagnosis, 31(12), 1147–1152. https://doi.org/10.1002/pd.2849
Gant, N. F., Daley, G. L., Chand, S., Whalley, P. J., & MacDonald, P. C. (1973). A study of angiotensin II pressor response throughout primigravid pregnancy. The Journal of clinical investigation, 52(11), 2682–2689. https://doi.org/10.1172/JCI107462
Gant, N. F., Chand, S., Worley, R. J., Whalley, P. J., Crosby, U. D., & MacDonald, P. C. (1974). A clinical test useful for predicting the development of acute hypertension in pregnancy. American journal of obstetrics and gynecology, 120(1), 1–7. https://doi.org/10.1016/0002-9378(74)90170-7
Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. (2020). Obstetrics and gynecology, 135(6), e237–e260. https://doi.org/10.1097/AOG.0000000000003891
Giguère, Y., Charland, M., Bujold, E., Bernard, N., Grenier, S., Rousseau, F., Lafond, J., Légaré, F., & Forest, J. C. (2010). Combining biochemical and ultrasonographic markers in predicting preeclampsia: a systematic review. Clinical chemistry, 56(3), 361–375. https://doi.org/10.1373/clinchem.2009.134080
Haugen, M., Brantsæter, A. L., Winkvist, A., Lissner, L., Alexander, J., Oftedal, B., Magnus, P., & Meltzer, H. M. (2014). Associations of pre-pregnancy body mass index and gestational weight gain with pregnancy outcome and postpartum weight retention: a prospective observational cohort study. BMC pregnancy and childbirth, 14, 201. https://doi.org/10.1186/1471-2393-14-201
Henderson, J. T., Thompson, J. H., Burda, B. U., & Cantor, A. (2017). Preeclampsia Screening: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA, 317(16), 1668–1683. https://doi.org/10.1001/jama.2016.18315
Heyborne, K. D., & Chism, D. M. (2000). Reversal of Ballantyne syndrome by selective second-trimester fetal termination. A case report. The Journal of reproductive medicine, 45(4), 360–362.
Hitti, J., Sienas, L., Walker, S., Benedetti, T. J., & Easterling, T. (2018). Contribution of hypertension to severe maternal morbidity. American journal of obstetrics and gynecology, 219(4), 405.e1–405.e7. https://doi.org/10.1016/j.ajog.2018.07.002
Kuklina, E. V., Ayala, C., & Callaghan, W. M. (2009). Hypertensive disorders and severe obstetric morbidity in the United States. Obstetrics and gynecology, 113(6), 1299–1306. https://doi.org/10.1097/AOG.0b013e3181a45b25
Lam, C., Lim, K. H., & Karumanchi, S. A. (2005). Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension (Dallas, Tex. : 1979), 46(5), 1077–1085. https://doi.org/10.1161/01.HYP.0000187899.34379.b0
Leslie, K., Thilaganathan, B., & Papageorghiou, A. (2011). Early prediction and prevention of pre-eclampsia. Best practice & research. Clinical obstetrics & gynaecology, 25(3), 343–354. https://doi.org/10.1016/j.bpobgyn.2011.01.002
Levine, R. J., Hauth, J. C., Curet, L. B., Sibai, B. M., Catalano, P. M., Morris, C. D., DerSimonian, R., Esterlitz, J. R., Raymond, E. G., Bild, D. E., Clemens, J. D., & Cutler, J. A. (1997). Trial of calcium to prevent preeclampsia. The New England journal of medicine, 337(2), 69–76. https://doi.org/10.1056/NEJM199707103370201
Levine, R. J., Thadhani, R., Qian, C., Lam, C., Lim, K. H., Yu, K. F., Blink, A. L., Sachs, B. P., Epstein, F. H., Sibai, B. M., Sukhatme, V. P., & Karumanchi, S. A. (2005). Urinary placental growth factor and risk of preeclampsia. JAMA, 293(1), 77–85. https://doi.org/10.1001/jama.293.1.77
Levine, R. J., Lam, C., Qian, C., Yu, K. F., Maynard, S. E., Sachs, B. P., Sibai, B. M., Epstein, F. H., Romero, R., Thadhani, R., Karumanchi, S. A., & CPEP Study Group (2006). Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. The New England journal of medicine, 355(10), 992–1005. https://doi.org/10.1056/NEJMoa055352
Lim, S., Li, W., Kemper, J., Nguyen, A., Mol, B. W., & Reddy, M. (2021). Biomarkers and the Prediction of Adverse Outcomes in Preeclampsia: A Systematic Review and Meta-analysis. Obstetrics and gynecology, 137(1), 72–81. https://doi.org/10.1097/AOG.0000000000004149
Lobo, G. A. R., Nowak, P. M., Panigassi, A. P., Lima, A. I. F., Araujo Júnior, E., Nardozza, L. M. M., & Pares, D. B. S. (2019). Validation of Fetal Medicine Foundation algorithm for prediction of pre-eclampsia in the first trimester in an unselected Brazilian population. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 32(2), 286–292. https://doi.org/10.1080/14767058.2017.1378332
Madala, D., Maktabi, M. A., Sabbagh, R., Erfani, H., Moon, A., & Van den Veyver, I. B. (2022). Lower fetal fraction in clinical cell-free DNA screening results is associated with increased risk of hypertensive disorders of pregnancy. Prenatal diagnosis, 42(10), 1253–1261. https://doi.org/10.1002/pd.6221
Meertens, L. J. E., Scheepers, H. C. J., van Kuijk, S. M. J., Aardenburg, R., van Dooren, I. M. A., Langenveld, J., van Wijck, A. M., Zwaan, I., Spaanderman, M. E. A., & Smits, L. J. M. (2019). External Validation and Clinical Usefulness of First Trimester Prediction Models for the Risk of Preeclampsia: A Prospective Cohort Study. Fetal diagnosis and therapy, 45(6), 381–393. https://doi.org/10.1159/000490385
Myatt, L., Clifton, R. G., Roberts, J. M., Spong, C. Y., Hauth, J. C., Varner, M. W., Wapner, R. J., Thorp, J. M., Jr, Mercer, B. M., Grobman, W. A., Ramin, S. M., Carpenter, M. W., Samuels, P., Sciscione, A., Harper, M., Tolosa, J. E., Saade, G., Sorokin, Y., Anderson, G. D., & Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU) (2012). The utility of uterine artery Doppler velocimetry in prediction of preeclampsia in a low-risk population. Obstetrics and gynecology, 120(4), 815–822. https://doi.org/10.1097/AOG.0b013e31826af7fb
Milne, F., Redman, C., Walker, J., Baker, P., Bradley, J., Cooper, C., de Swiet, M., Fletcher, G., Jokinen, M., Murphy, D., Nelson-Piercy, C., Osgood, V., Robson, S., Shennan, A., Tuffnell, A., Twaddle, S., & Waugh, J. (2005). The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community. BMJ (Clinical research ed.), 330(7491), 576–580. https://doi.org/10.1136/bmj.330.7491.576
Mosimann, B., Pfiffner, C., Amylidi-Mohr, S., Risch, L., Surbek, D., & Raio, L. (2017). First trimester combined screening for preeclampsia and small for gestational age - a single centre experience and validation of the FMF screening algorithm. Swiss medical weekly, 147, w14498. https://doi.org/10.4414/smw.2017.14498
Mosimann, B., Amylidi-Mohr, S. K., Surbek, D., & Raio, L. (2020). FIRST TRIMESTER SCREENING FOR PREECLAMPSIA - A SYSTEMATIC REVIEW. Hypertension in pregnancy, 39(1), 1–11. https://doi.org/10.1080/10641955.2019.1682009
Moufarrej, M. N., Vorperian, S. K., Wong, R. J., Campos, A. A., Quaintance, C. C., Sit, R. V., Tan, M., Detweiler, A. M., Mekonen, H., Neff, N. F., Baruch-Gravett, C., Litch, J. A., Druzin, M. L., Winn, V. D., Shaw, G. M., Stevenson, D. K., & Quake, S. R. (2022). Early prediction of preeclampsia in pregnancy with cell-free RNA. Nature, 602(7898), 689–694. https://doi.org/10.1038/s41586-022-04410-z
Myatt, L., Clifton, R. G., Roberts, J. M., Spong, C. Y., Hauth, J. C., Varner, M. W., Wapner, R. J., Thorp, J. M., Jr, Mercer, B. M., Grobman, W. A., Ramin, S. M., Carpenter, M. W., Samuels, P., Sciscione, A., Harper, M., Tolosa, J. E., Saade, G., Sorokin, Y., Anderson, G. D., & Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Network (MFMU) (2012). The utility of uterine artery Doppler velocimetry in prediction of preeclampsia in a low-risk population. Obstetrics and gynecology, 120(4), 815–822. https://doi.org/10.1097/AOG.0b013e31826af7fb
Oliveira, N., Magder, L. S., Blitzer, M. G., & Baschat, A. A. (2014). First-trimester prediction of pre-eclampsia: external validity of algorithms in a prospectively enrolled cohort. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 44(3), 279–285. https://doi.org/10.1002/uog.13435
O'Gorman, N., Wright, D., Poon, L. C., Rolnik, D. L., Syngelaki, A., Wright, A., Akolekar, R., Cicero, S., Janga, D., Jani, J., Molina, F. S., de Paco Matallana, C., Papantoniou, N., Persico, N., Plasencia, W., Singh, M., & Nicolaides, K. H. (2017). Accuracy of competing-risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 49(6), 751–755. https://doi.org/10.1002/uog.17399
Park, F. J., Leung, C. H., Poon, L. C., Williams, P. F., Rothwell, S. J., & Hyett, J. A. (2013). Clinical evaluation of a first trimester algorithm predicting the risk of hypertensive disease of pregnancy. The Australian & New Zealand journal of obstetrics & gynaecology, 53(6), 532–539. https://doi.org/10.1111/ajo.12126
Peraçoli, J. C., Borges, V. T. M., Ramos, J. G. L., Cavalli, R. C., Costa, S. H. A. M., Oliveira, L. G., Souza, F. L. P., Korkes, H. A., Brum, I. R., Costa, M. L., Corrêa Junior, M. D., Sass, N., Diniz, A. L. D., Prado, C. A. C., & Cunha Filho, E. V. D. (2019). Pre-eclampsia/Eclampsia. Pré-eclâmpsia/Eclâmpsia. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 41(5), e1–e2. https://doi.org/10.1055/s-0040-1702167
Phipps, E. A., Thadhani, R., Benzing, T., & Karumanchi, S. A. (2019). Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nature reviews. Nephrology, 15(5), 275–289. https://doi.org/10.1038/s41581-019-0119-6
Podymow, T., & August, P. (2010). Postpartum course of gestational hypertension and preeclampsia. Hypertension in pregnancy, 29(3), 294–300. https://doi.org/10.3109/10641950902777747
Poon, L. C., Shennan, A., Hyett, J. A., Kapur, A., Hadar, E., Divakar, H., McAuliffe, F., da Silva Costa, F., von Dadelszen, P., McIntyre, H. D., Kihara, A. B., Di Renzo, G. C., Romero, R., D'Alton, M., Berghella, V., Nicolaides, K. H., & Hod, M. (2019). The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia: A pragmatic guide for first-trimester screening and prevention. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 145 Suppl 1(Suppl 1), 1–33. https://doi.org/10.1002/ijgo.12802
Qin, S., Sun, N., Xu, L., Xu, Y., Tang, Q., Tan, L., Chen, A., Zhang, L., & Liu, S. (2022). The Value of Circulating microRNAs for Diagnosis and Prediction of Preeclampsia: a Meta-analysis and Systematic Review. Reproductive sciences (Thousand Oaks, Calif.), 29(11), 3078–3090. https://doi.org/10.1007/s43032-021-00799-6
Roberts, J. M., & Gammill, H. S. (2005). Preeclampsia: recent insights. Hypertension (Dallas, Tex. : 1979), 46(6), 1243–1249. https://doi.org/10.1161/01.HYP.0000188408.49896.c5
Robinson, C. J., & Johnson, D. D. (2007). Soluble endoglin as a second-trimester marker for preeclampsia. American journal of obstetrics and gynecology, 197(2), 174.e1–174.e1745. https://doi.org/10.1016/j.ajog.2007.03.058
Sibai B. M. (1988). Pitfalls in diagnosis and management of preeclampsia. American journal of obstetrics and gynecology, 159(1), 1–5. https://doi.org/10.1016/0002-9378(88)90482-6
Skjaerven, R., Wilcox, A. J., & Lie, R. T. (2002). The interval between pregnancies and the risk of preeclampsia. The New England journal of medicine, 346(1), 33–38. https://doi.org/10.1056/NEJMoa011379
Tan, M. Y., Syngelaki, A., Poon, L. C., Rolnik, D. L., O'Gorman, N., Delgado, J. L., Akolekar, R., Konstantinidou, L., Tsavdaridou, M., Galeva, S., Ajdacka, U., Molina, F. S., Persico, N., Jani, J. C., Plasencia, W., Greco, E., Papaioannou, G., Wright, A., Wright, D., & Nicolaides, K. H. (2018). Screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 52(2), 186–195. https://doi.org/10.1002/uog.19112
Thangaratinam, S., Ismail, K. M., Sharp, S., Coomarasamy, A., Khan, K. S., & Tests in Prediction of Pre-eclampsia Severity review group (2006). Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review. BJOG : an international journal of obstetrics and gynaecology, 113(4), 369–378. https://doi.org/10.1111/j.1471-0528.2006.00908.x
Tranquilli, A. L., Brown, M. A., Zeeman, G. G., Dekker, G., & Sibai, B. M. (2013). The definition of severe and early-onset preeclampsia. Statements from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Pregnancy hypertension, 3(1), 44–47. https://doi.org/10.1016/j.preghy.2012.11.001
Urato, A. C., Bond, B., Craigo, S. D., Norwitz, E. R., Paulus, J. K., & Strohsnitter, W. C. (2012). Admission uric acid levels and length of expectant management in preterm preeclampsia. Journal of perinatology : official journal of the California Perinatal Association, 32(10), 757–762. https://doi.org/10.1038/jp.2011.187
US Preventive Services Task Force, Bibbins-Domingo, K., Grossman, D. C., Curry, S. J., Barry, M. J., Davidson, K. W., Doubeni, C. A., Epling, J. W., Jr, Kemper, A. R., Krist, A. H., Kurth, A. E., Landefeld, C. S., Mangione, C. M., Phillips, W. R., Phipps, M. G., Silverstein, M., Simon, M. A., & Tseng, C. W. (2017). Screening for Preeclampsia: US Preventive Services Task Force Recommendation Statement. JAMA, 317(16), 1661–1667. https://doi.org/10.1001/jama.2017.3439
Wallis, A. B., Saftlas, A. F., Hsia, J., & Atrash, H. K. (2008). Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004. American journal of hypertension, 21(5), 521–526. https://doi.org/10.1038/ajh.2008.20
Velauthar, L., Plana, M. N., Kalidindi, M., Zamora, J., Thilaganathan, B., Illanes, S. E., Khan, K. S., Aquilina, J., & Thangaratinam, S. (2014). First-trimester uterine artery Doppler and adverse pregnancy outcome: a meta-analysis involving 55,974 women. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 43(5), 500–507. https://doi.org/10.1002/uog.13275
Verlohren, S., Brennecke, S. P., Galindo, A., Karumanchi, S. A., Mirkovic, L. B., Schlembach, D., Stepan, H., Vatish, M., Zeisler, H., & Rana, S. (2022). Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia. Pregnancy hypertension, 27, 42–50. https://doi.org/10.1016/j.preghy.2021.12.003
von Dadelszen, P., Payne, B., Li, J., Ansermino, J. M., Broughton Pipkin, F., Côté, A. M., Douglas, M. J., Gruslin, A., Hutcheon, J. A., Joseph, K. S., Kyle, P. M., Lee, T., Loughna, P., Menzies, J. M., Merialdi, M., Millman, A. L., Moore, M. P., Moutquin, J. M., Ouellet, A. B., Smith, G. N., … PIERS Study Group (2011). Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model. Lancet (London, England), 377(9761), 219–227. https://doi.org/10.1016/S0140-6736(10)61351-7
Yancey, L. M., Withers, E., Bakes, K., & Abbott, J. (2011). Postpartum preeclampsia: emergency department presentation and management. The Journal of emergency medicine, 40(4), 380–384. https://doi.org/10.1016/j.jemermed.2008.02.056
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