Atividade antibacteriana de membranas de PVA impregnadas com quitosana e óxido de zinco

Autores

DOI:

https://doi.org/10.33448/rsd-v12i3.40720

Palavras-chave:

Membranas; Biomateriais; Superfícies e interfaces; Misturas.

Resumo

O desenvolvimento de alternativas aos antibióticos convencionais contra superbactérias representa um passo importante para evitar o aumento da resistência das bactérias diante dos tratamentos convencionais. Neste trabalho, avaliou-se a influência de diferentes combinações de dois componentes antibacterianos ativos (quitosana e óxido de zinco) e uma matriz de álcool polivinílico (PVA) em membranas produzidas pela técnica de evaporação de solvente. Esses sistemas foram avaliados em termos de inativação do biofilme, ensaios de tempo de morte e halos de inibição contra S. aureus (ATCC 25923) em membranas que devem liberar componentes reativos, preservando a integridade do material e favorecendo a geração de espécies reativas para melhorar a atividade antibacteriana. Os resultados sugerem o potencial da combinação de quitosana, óxido de zinco e álcool polivinílico para inibir o crescimento de S. aureus, uma vez que o PVA melhorou a dispersão dos componentes, enquanto o quelato de quitosana-ZnO melhora a atividade mútua do óxido metálico e do polímero natural.

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14/03/2023

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CAVALCANTE, E. H. M. .; SILVA JUNIOR, F. A. G. da .; PEREIRA, M. A. T. .; PEREIRA, P. J. .; COSTA, M. M. da .; OLIVEIRA, H. P. de . Atividade antibacteriana de membranas de PVA impregnadas com quitosana e óxido de zinco. Research, Society and Development, [S. l.], v. 12, n. 3, p. e23812340720, 2023. DOI: 10.33448/rsd-v12i3.40720. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/40720. Acesso em: 22 dez. 2024.

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v. 12 n. 3

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Ciências Exatas e da Terra

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Copyright (c) 2023 Edmo Henrique Martins Cavalcante; Fernando Antônio Gomes da Silva Junior; Monica Aparecida Tomé Pereira; Paulo José Pereira; Mateus Matiuzzi da Costa; Helinando Pequeno de Oliveira

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