Comorbidades neuropsiquiátricas e cognitivas na epilepsia

Autores

DOI:

https://doi.org/10.33448/rsd-v12i10.43331

Palavras-chave:

Comorbidade; Epilepsia; Neurologia.

Resumo

A crise epiléptica é caracterizada por um episódio momentâneo de sinais e sintomas que são causados por atividade neuronal anormal, excessiva ou sincrônica no cérebro. Por outro lado, a síndrome epiléptica é definida, de acordo com a Liga Internacional contra a Epilepsia (ILAE), por "um grupo de características clínicas e de neuroimagem em achados eletroencefalográficos (EEG), muitas vezes, apoiados por achados etiológicos específicos (estruturais, genéticos, metabólicos, imunológicos e infecciosos)". Dessa forma, os pacientes com epilepsia apresentam múltiplas comorbidades neuropsiquiátricas, sendo os transtornos depressivos os mais comuns, condição que afeta a qualidade de vida e é influenciada por inúmeros fatores externos. O presente estudo objetiva realizar uma revisão da literatura baseada na análise de artigos publicados de 2010 a 2022 nas bases de dados PubMed (Medline) e Science Direct sobre epilepsia, seu comprometimento cognitivo e suas comorbidades neuropsiquiátricas, utilizando a terminologia indicada pelo Sistema de Descritores em Ciências da Saúde (DeCS) e um conjunto de critérios predeterminados para selecionar os melhores artigos sobre o tema. Portanto, a abordagem das comorbidades psiquiátricas, como os transtornos depressivos e as deficiências cognitivas, na epilepsia é essencial, tendo em vista sua alta prevalência e as repercussões negativas na vida do paciente. Consequentemente, são necessários estudos mais aprofundados para oferecer um melhor prognóstico aos pacientes com epilepsia e avaliar os efeitos colaterais e as repercussões clínicas dos medicamentos antiepilépticos (AEDs).

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04/10/2023

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AGUIAR, A. B. .; AGUIAR, A. B. .; ALBUQUERQUE FILHO, L. B. de .; RAMANZINI, L. G. .; SILVA, J. G. M. da .; LIMA, M. P. P. .; RIBAS, M. Z. .; PATICCIÉ, G. F. .; NOLETO, F. M. .; SANTOS, J. C. C. dos . Comorbidades neuropsiquiátricas e cognitivas na epilepsia. Research, Society and Development, [S. l.], v. 12, n. 10, p. e33121043331, 2023. DOI: 10.33448/rsd-v12i10.43331. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/43331. Acesso em: 22 nov. 2024.

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Ciências da Saúde