Vitamina D e doenças infectocontagiosas na pandemia da COVID-19

Autores

DOI:

https://doi.org/10.33448/rsd-v9i7.4614

Palavras-chave:

SARS; Coronavírus; Tratamento; H1N1; Influenza.

Resumo

A pandemia da doença do novo coronavírus (COVID-19) surgiu no fim de 2019 em Wuhan, China, e rapidamente se alastrou ao redor de todo o globo. Considerando sua rápida taxa de transmissão, a COVID-19 tornou-se uma ameaça à saúde pública mundial. Portanto, ideias objetivas baseadas em evidências científicas devem ser propostas para o tratamento de pacientes infectados. A vitamina D é um hormônio que apresenta função importante na regulação da função do sistema imune. As principais fontes de obtenção da Vitamina D são a alimentação e do processo de síntese no organismo iniciado na pele,  através de fotorreação mediada pela luz solar, em que a pré-vitamina D isomeriza-se em pró-vitamina D. Posteriormente, é metabolizada no fígado em 25-hidroxivitamina D, e convertida no rim em sua forma ativa,  a 1,25-dihidroxivitamina D. Por conta do seu papel chave na melhoria da resposta imune, a Vitamina D pode afetar positivamente o tratamento de diversas doenças infectocontagiosas, tais como a influenza e H1N1. Esta revisão tem como objetivo informar sobre o uso de Vitamina D como possível aliado no tratamento da COVID-19. Os estudos incluídos nesta revisão apontam que a vitamina D pode exercer funções imunomoduladoras e anti-inflamatórias, que beneficiam significativamente o tratamento de infecções virais. Recomenda-se que ensaios clínicos randomizados e estudos populacionais amplos sejam conduzidos para melohr elucidar o papel efetivo da Vitamina D no tratamento de pacientes com COVID-19.

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12/06/2020

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SILVINO, V. O.; PEREIRA, M. M. L.; MOURA, R. C. de; BATISTA, M. C. C.; ROSA, B. V.; MOURA, E. H. de; MARTINS, M. do C. C. e; SANTOS, M. A. P. dos. Vitamina D e doenças infectocontagiosas na pandemia da COVID-19. Research, Society and Development, [S. l.], v. 9, n. 7, p. e771974614, 2020. DOI: 10.33448/rsd-v9i7.4614. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/4614. Acesso em: 17 jul. 2024.

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v. 9 n. 7

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Ciências da Saúde

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