Effects of water-soluble extract of açaí (Euterpe oleracea Mart.) on Wistar rats with induced obesity, diabetes, and cholesterol
DOI:
https://doi.org/10.33448/rsd-v10i13.20981Keywords:
Glycemic indexAbstract
Among the countless species found in the Amazon biome, açaí is valued for its characteristic flavor and high nutrient content; in particular, it has a high content of anthocyanins. The present study aimed to evaluate the effect of the water-soluble extract of açaí in rats induced to obesity, diabetes and cholesterol, being administered monosodium glutamate at a concentration of 4 mg/g of animal weight alloxan mg/kg in 0.9% salina by intraperitoneally. For the biological tests, these were composed with a total of 50 animals, divided into 10 groups, composed of 5 rodents each. The control group consisted of healthy rats fed on commercial food. The determination of the proximal composition, dietary fiber and anthocyanin in the açaí extract was carried out. This extract was then supplemented in the feed for the different types of model animals that remained in feedlot for 28 days. The characterization of the açaí extract revealed high levels of insoluble dietary fiber (3.31 g / 100 g) and anthocyanin (45 mg / 100 g). There was also a positive effect on feed supplementation during the 28 days of confinement, with a reduction in weight and glycemic index observed in animals (p < 0.05).
References
Association of Official Agricultural Chemists – AOAC. 2012. Official Methods of the Association of the Agricultural Chemists. Washington, DC, usa: AOAC.
Almeida, M .M. B.; Sousa, P. H. M.; Arriaga, A. M. C.; Prado, G. M.; Magalhaes, C. E. C.; Maia, G. A.; & Lemos, T. L .G. (2011) Bioactive compounds and antioxidant activity of fresh exotic fruits from northeastern Brazil. Food Research International, 44, 2155–2159.
Basu, A., Du, M., Leyva, M. J., Sanchez, K., Betts, N. M, Wu, M. et al. (2010). Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. Journal of Nutrition, 140, 1582–1587.
Bobbio, F. O.; Druzian, J. I.; Abrão, P. A.; Bobbio, P. A.; & Fadelli, S. (2000). Identificação e quantificação das antocianinas do fruto do açaizeiro (Euterpe oleracea) Mart. Ciência e Tecnologia de Alimentos. 20, 388–390.
Coutinho, R. M. P.; Fontes, E. A. F.; Vieira, L. M.; Barros, F. A. R. D.; Carvalho, A. F. D.; & Stringheta, P. C. Physicochemical and microbiological characterization and antioxidant capacity of açaí pulps marketed in the states of Minas Gerais and Pará, Brazil. Ciência Rural, 47, 1, e20151172, 2017. http://dx.doi. org/10.1590/0103-8478cr20151172.
De Rosso, V. V.; & Mercadante, A. Z. (2007) Identification And Quantification Of Carotenoids, By HPLCPDA-MS/MS, From Amazonian Fruits. Journal of Agricultural And Food Chemistry, Washington, 55, 5062–5072.
Devalaraja, S.; Jain; S.; & Yadav, H. (2011) Exotic fruits as therapeutic complements for diabetes, obesity and metabolic syndrome. Food Research International 44, 1856–1865. http://dx.doi.org/10.1016/j.foodres.2011.04.008. PMid:21857774.
Ferreira, D. F. Sisvar: sistema de análise de variância. Versão 5.3. Lavras: Ufla, 2010.
Fernandes, E. T. M. B.; Maciel, V. T.; Souza, M. L. D.; Furtado, C. D. M.; Wadt, L. H. D. O.; & Cunha, C. R. D. (2016) Physicochemical composition, color and sensory acceptance of low-fat cupuaçu and açaí nectar: characterization and changes during storage. Food Science and Technology, 36, 413–420. http://dx.doi.org/10.1590/1678-457X.03415.
Fung T T, Hu F B, Pereira M A, Liu S, Stampfer M J, Colditz G A, & Willet W C (2002). Whole-grain intake and the risk of type 2 diabetes: a prospective study in men. American Journal of Clinical Nutrition 76, 535–540.
Li, D., Zhang, Y., Liu, Y., Sun, R., & Xia, M. (2015) Purified anthocyanin supplementation reduces dyslipidemia, enhances antioxidant capacity, and prevents insulin resistance in diabetic patients. Journal of Nutrition, 145, 742–748.
Kim, J. Y.; Hong, J. H.; Jung, H. K.; Jeong, Y. S.; & Cho K. H. (2012) Grape skin and loquat leaf extracts and acai puree have potent anti-atherosclerotic and anti-diabetic activity in vitro and in vivo in hypercholesterolemic zebrafish. International Journal of Molecular Medicine, 30, 606–614, 2012. http://dx.doi. org/10.3892/ijmm.2012.1045. PMid:22751734.
Masella, R.; Santangelo, C.; D’archivo, M.; Livolti, G.; Giovanni, C.; & Galvano, F (2012). Protocatechuic acid and human disease prevention: biological activities and molecular mechanisms. Current Medicinal Chemistry, 19, 2901–2917. http://dx.doi.org/10.2174/092986712800672102. PMid:22519395.
Menezes, F. S., Falcão, D. Q., Filho. R. F .W. M., Silveira, C. S., & Rennó, M. N. (2005). Chemical and pharmacological survey on Brazilian medicinal plants using ethnopharmacological Iinformation as a tool. Acta Hort, 675.
McLellan, K. C. P. (2007). Diabetes Mellitus do Tipo 2, Sindrome Metabolica e Modificação no Estilo de Vida. Resvista de Nutrição. 20, 5. Campinas.
Rockenbach, I. I.; Rodrigues, E.; Gonzaga, L.V.; Caliari, V.; Genoveze, M .I.; Gonçalves, A. E. S. S.; & Fettett, R. (2011) Phenolic compounds content and antioxidant activity in pomace from selectedred grapes (Vitis vinifera L. and Vitis labrusca L.) widely produced in Brazil. Food Chemistry, 127, 174–179.
Rufino, M. M. S.; Alves, R. E.; Brito, E. S.; Pérez-Jimenez, J.; Saura-Calixto, F.; & Mancini-Filho, J. (2010) Bioactive compounds and antioxidant capacities of 18 non-traditional tropical fruits from Brazil. Food Chemistry, 121, 996–1002, 2010. http://dx.doi.org/10.1016/j.foodchem.2010.01.037.
Samuel Wu Y H, Chiu C H, Yang DJ , Lin Y L, Tseng J K, & Chen Y C. (2013). Inhibitory effects of litchi (Litchi chinensis Sonn) flower water extracts on lipase activity and diet-induced obesity. Journal of Functionals Foods, 5, 923–929. Doi:10.1016/j.jff.2013.02.002.
Santos Buelga C, Mateus N, & de Freitas V. Anthocyanins. Plant pigments and beyond. J.Agric. Food Chem. 2014;62(29):6879‐6884.
Severino, C.; Brizzi, P.; Soolinas, A.; Secchi, G.; Maioli, M.; & Tonolo, G. (2002) Low-dose dexamethasone in the rat. A model to study insulin resistance. American Journal of Physiology, 283, E367–E373.
Sousa, M. S. B.; Vieira, L. M.; Silva, M. J. M.; & Lima, A. (2011) Caracterização nutricional e compostos antioxidantes em subprodutos de polpas de frutas tropicais. Ciência e agrotecnologia, 35, 554–559.
Titta L, Trinei M, Stendardo M, Berniakovivh I, Petroni K, Tonelli C, Riso P, Porrini M, Minucci S, Pelicci P G, Rapisarda P, Recupero G R, & Giorgo M. (2009). Blood Orange juice inhibits fat accumulation in mice. International Journal of Obesity, 34, 578–588. Doi: 10.1038/ijo.2009.266.
Udani, J. K., Singh B. B., Singh, I. J. & & Barrett, M. L. (2011). Effects of Açai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: A pilot study. Nutrition Journal, 10, 2–7.
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