Enterococcus faecium EF137V: una nueva fuente estratégica para el control de la salud humana y animal contra especies de Campylobacter
DOI:
https://doi.org/10.33448/rsd-v9i10.8853Palabras clave:
Probióticos; Enterococcus faecium; Campylobacter jejuni; Campylobacter coli; Biotecnología.Resumen
El probiótico está relacionado con un complemento alimenticio, mientras que los productos bioterapéuticos vivos, los PBV se consideran medicamentos biológicos, ambos contienen microorganismos vivos con sustancias activas que benefician al huésped. Enterococcus faecium tiene muchas propiedades interesantes y funcionales para la salud humana y animal, incluida la capacidad antimicrobiana, que ayuda en enfermedades de intoxicación alimentaria como la campilobacteriosis. En este contexto se han descrito especies de Campylobacter jejuni y C. coli. Por lo tanto, ante la necesidad de desarrollar alternativas para asegurar la inocuidad de los productos consumidos por la población, este trabajo propone una estrategia complementaria para reducir o eliminar Campylobacter mediante el uso de Enterococcus faecium EF137V, aislado de queso “Coalho” artesanal de Pernambuco-Brasil. Los análisis se realizaron in vitro. Dadas las condiciones adversas, como pH ácido y presencia de sales biliares, en las que se expuso EF137V, se encontró que la bacteria presentaba resistencia a afecciones gastrointestinales, adherencia a células epiteliales, actividad antimicrobiana por sus compuestos metabólicos frente a cepas de referencia de C. jejuni y C. coli, así como actividad antagónica, lo que sugiere que ambas especies no podrán crecer desordenadamente en la microbiota intestinal del hospedador, pudiendo así controlar estos microorganismos en la comunidad bacteriana en pollos de engorde y prevenir nuevas infecciones en humanos. Se puede concluir que el EF137V es un PVB y probiótico prometedor, presentando gran capacidad para aplicaciones biotecnológicas.
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Derechos de autor 2020 Priscilla Régia de Andrade Calaça; Elaine Cristina da Silva; Felipe Pereira de Melo; Dayane da Silva Santos; Ana Beatriz Lins Aragão; Pablo Eugênio da Costa e Silva; Mércia Rodrigues Barros; Ana Lúcia Figueiredo Porto; Maria Taciana Cavalcanti Vieira Soares
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